Achieving comprehensive remission or low disease activity in rheumatoid patients and its impact on workability – Saudi Rheumatoid Arthritis Registry

Achieving comprehensive remission or low disease activity in rheumatoid patients and its impact on workability – Saudi Rheumatoid Arthritis Registry

Hani Almoallim,1–3 Nahid Janoudi,2 Fahdah Alokaily,4 Zeyad Alzahrani,5 Shereen Algohary,3 Hanan Alosaimi,3,6 Suzan Attar3,7 1Department of Medicine, Faculty of Medicine, Umm Alqura University, Makkah, Saudi Arabia; 2Department of Medicine, Dr. Soliman Fakeeh Hospital, Jeddah, Saudi Arabia;...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Almoallim H, Janoudi N, Alokaily F, Alzahrani Z, Algohary S, Alosaimi H, Attar S
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2019
Materias:
Rheumatoid arthritis
work impairment
WPAI score
disease activity
HAQ score
VAS score
Diseases of the musculoskeletal system
RC925-935
Acceso en línea:https://doaj.org/article/506dc31cf4ba45e18a36ce4de4911310
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:506dc31cf4ba45e18a36ce4de4911310
record_format dspace
spelling oai:doaj.org-article:506dc31cf4ba45e18a36ce4de49113102021-12-02T03:57:30ZAchieving comprehensive remission or low disease activity in rheumatoid patients and its impact on workability – Saudi Rheumatoid Arthritis Registry1179-156Xhttps://doaj.org/article/506dc31cf4ba45e18a36ce4de49113102019-04-01T00:00:00Zhttps://www.dovepress.com/achieving-comprehensive-remission-or-low-disease-activity-in-rheumatoi-peer-reviewed-article-OARRRhttps://doaj.org/toc/1179-156XHani Almoallim,1–3 Nahid Janoudi,2 Fahdah Alokaily,4 Zeyad Alzahrani,5 Shereen Algohary,3 Hanan Alosaimi,3,6 Suzan Attar3,7 1Department of Medicine, Faculty of Medicine, Umm Alqura University, Makkah, Saudi Arabia; 2Department of Medicine, Dr. Soliman Fakeeh Hospital, Jeddah, Saudi Arabia; 3Alzaidi Chair of Research in Rheumatic Diseases, Umm Alqura University, Makkah, Saudi Arabia; 4Division of Rheumatology, Department of Medicine, Prince Sultan Military Medical City, Riyadh, Saudi Arabia; 5Department of Medicine, Faculty of King Saud bin Abdulaziz for Health Sciences, Jeddah, Saudi Arabia; 6Department of Medicine, King Fahd Armed Forces Hospital, Jeddah, Saudi Arabia; 7Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia Purpose: Ability to work is an important endpoint in rheumatoid arthritis (RA). It is not clear what outcome measures should be used to guide treatment in order to maximize workability. This study addressed the impact of RA on workability in a Saudi population and examined the correlation between objective measures of disease activity and reduced workability. This will allow better understanding of treatment targets that will translate into improved workability. Patients and methods: Data were collected through a digital patient record keeper: The Rheumatoid Arthritis Saudi Database. Male and female patients, ≥18 years of age, that met the American College for Rheumatology criteria for diagnosis of RA, were recruited, regardless of treatment. Demographic and disease-specific data were collected. Disease Activity Score-28 (DAS-28) was used to define patients as low (DAS-28 ≤3.2) vs high (DAS-28 >3.2) disease activity. Health assessment questionnaire (HAQ) score, visual analog scale (VAS) score, and musculoskeletal ultrasound 7 joint score were documented also. The work productivity and activity impairment (WPAI) score was used to measure absenteeism, presenteeism, overall work impairment, and activity impairment. DAS-28 score was correlated with WPAI score and linear regression used to identify the demographic and measures of treatment response that predict improvement in WPAI score. Results: Higher absenteeism and more activity impairment were seen for patients with persistent DAS-28 >3.2 (non-achievers). HAQ and VAS scores correlated with presenteeism, overall work impairment, and activity impairment. Conclusion: Disease activity, as defined by DAS-28 score, correlates with absenteeism and work impairment in a Saudi population. However, on linear regression analysis, HAQ and VAS scores were the only measures predictive of work impairment. These scores should be used to monitor response to treatment regimens that aim to maximize work potential for Saudi individuals. Keywords: rheumatoid arthritis, work impairment, WPAI score, disease activity, HAQ score, VAS scoreAlmoallim HJanoudi NAlokaily FAlzahrani ZAlgohary SAlosaimi HAttar SDove Medical PressarticleRheumatoid arthritiswork impairmentWPAI scoredisease activityHAQ scoreVAS scoreDiseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol Volume 11, Pp 89-95 (2019)
institution DOAJ
collection DOAJ
language EN
topic Rheumatoid arthritis
work impairment
WPAI score
disease activity
HAQ score
VAS score
Diseases of the musculoskeletal system
RC925-935
spellingShingle Rheumatoid arthritis
work impairment
WPAI score
disease activity
HAQ score
VAS score
Diseases of the musculoskeletal system
RC925-935
Almoallim H
Janoudi N
Alokaily F
Alzahrani Z
Algohary S
Alosaimi H
Attar S
Achieving comprehensive remission or low disease activity in rheumatoid patients and its impact on workability – Saudi Rheumatoid Arthritis Registry
description Hani Almoallim,1–3 Nahid Janoudi,2 Fahdah Alokaily,4 Zeyad Alzahrani,5 Shereen Algohary,3 Hanan Alosaimi,3,6 Suzan Attar3,7 1Department of Medicine, Faculty of Medicine, Umm Alqura University, Makkah, Saudi Arabia; 2Department of Medicine, Dr. Soliman Fakeeh Hospital, Jeddah, Saudi Arabia; 3Alzaidi Chair of Research in Rheumatic Diseases, Umm Alqura University, Makkah, Saudi Arabia; 4Division of Rheumatology, Department of Medicine, Prince Sultan Military Medical City, Riyadh, Saudi Arabia; 5Department of Medicine, Faculty of King Saud bin Abdulaziz for Health Sciences, Jeddah, Saudi Arabia; 6Department of Medicine, King Fahd Armed Forces Hospital, Jeddah, Saudi Arabia; 7Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia Purpose: Ability to work is an important endpoint in rheumatoid arthritis (RA). It is not clear what outcome measures should be used to guide treatment in order to maximize workability. This study addressed the impact of RA on workability in a Saudi population and examined the correlation between objective measures of disease activity and reduced workability. This will allow better understanding of treatment targets that will translate into improved workability. Patients and methods: Data were collected through a digital patient record keeper: The Rheumatoid Arthritis Saudi Database. Male and female patients, ≥18 years of age, that met the American College for Rheumatology criteria for diagnosis of RA, were recruited, regardless of treatment. Demographic and disease-specific data were collected. Disease Activity Score-28 (DAS-28) was used to define patients as low (DAS-28 ≤3.2) vs high (DAS-28 >3.2) disease activity. Health assessment questionnaire (HAQ) score, visual analog scale (VAS) score, and musculoskeletal ultrasound 7 joint score were documented also. The work productivity and activity impairment (WPAI) score was used to measure absenteeism, presenteeism, overall work impairment, and activity impairment. DAS-28 score was correlated with WPAI score and linear regression used to identify the demographic and measures of treatment response that predict improvement in WPAI score. Results: Higher absenteeism and more activity impairment were seen for patients with persistent DAS-28 >3.2 (non-achievers). HAQ and VAS scores correlated with presenteeism, overall work impairment, and activity impairment. Conclusion: Disease activity, as defined by DAS-28 score, correlates with absenteeism and work impairment in a Saudi population. However, on linear regression analysis, HAQ and VAS scores were the only measures predictive of work impairment. These scores should be used to monitor response to treatment regimens that aim to maximize work potential for Saudi individuals. Keywords: rheumatoid arthritis, work impairment, WPAI score, disease activity, HAQ score, VAS score
format article
author Almoallim H
Janoudi N
Alokaily F
Alzahrani Z
Algohary S
Alosaimi H
Attar S
author_facet Almoallim H
Janoudi N
Alokaily F
Alzahrani Z
Algohary S
Alosaimi H
Attar S
author_sort Almoallim H
title Achieving comprehensive remission or low disease activity in rheumatoid patients and its impact on workability – Saudi Rheumatoid Arthritis Registry
title_short Achieving comprehensive remission or low disease activity in rheumatoid patients and its impact on workability – Saudi Rheumatoid Arthritis Registry
title_full Achieving comprehensive remission or low disease activity in rheumatoid patients and its impact on workability – Saudi Rheumatoid Arthritis Registry
title_fullStr Achieving comprehensive remission or low disease activity in rheumatoid patients and its impact on workability – Saudi Rheumatoid Arthritis Registry
title_full_unstemmed Achieving comprehensive remission or low disease activity in rheumatoid patients and its impact on workability – Saudi Rheumatoid Arthritis Registry
title_sort achieving comprehensive remission or low disease activity in rheumatoid patients and its impact on workability – saudi rheumatoid arthritis registry
publisher Dove Medical Press
publishDate 2019
url https://doaj.org/article/506dc31cf4ba45e18a36ce4de4911310
work_keys_str_mv AT almoallimh achievingcomprehensiveremissionorlowdiseaseactivityinrheumatoidpatientsanditsimpactonworkabilityndashsaudirheumatoidarthritisregistry
AT janoudin achievingcomprehensiveremissionorlowdiseaseactivityinrheumatoidpatientsanditsimpactonworkabilityndashsaudirheumatoidarthritisregistry
AT alokailyf achievingcomprehensiveremissionorlowdiseaseactivityinrheumatoidpatientsanditsimpactonworkabilityndashsaudirheumatoidarthritisregistry
AT alzahraniz achievingcomprehensiveremissionorlowdiseaseactivityinrheumatoidpatientsanditsimpactonworkabilityndashsaudirheumatoidarthritisregistry
AT algoharys achievingcomprehensiveremissionorlowdiseaseactivityinrheumatoidpatientsanditsimpactonworkabilityndashsaudirheumatoidarthritisregistry
AT alosaimih achievingcomprehensiveremissionorlowdiseaseactivityinrheumatoidpatientsanditsimpactonworkabilityndashsaudirheumatoidarthritisregistry
AT attars achievingcomprehensiveremissionorlowdiseaseactivityinrheumatoidpatientsanditsimpactonworkabilityndashsaudirheumatoidarthritisregistry
_version_ 1718401547722817536

Ejemplares similares