Actuation enhances patterning in human neural tube organoids

Actuation enhances patterning in human neural tube organoids

Mechanical forces, along with gene regulatory networks and cell-cell signalling, play an important role in the complex organization of tissues. Here the authors describe devices that actively apply mechanical force to developing neural tube, demonstrating that mechanical forces increase growth and e...

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Bibliographic Details
Main Authors: Abdel Rahman Abdel Fattah, Brian Daza, Gregorius Rustandi, Miguel Ángel Berrocal-Rubio, Benjamin Gorissen, Suresh Poovathingal, Kristofer Davie, Jorge Barrasa-Fano, Mar Cóndor, Xuanye Cao, Derek Hadar Rosenzweig, Yunping Lei, Richard Finnell, Catherine Verfaillie, Maurilio Sampaolesi, Peter Dedecker, Hans Van Oosterwyck, Stein Aerts, Adrian Ranga
Format: article
Language:EN
Published: Nature Portfolio 2021
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Science
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Online Access:https://doaj.org/article/506e1172f48248a2922027f6f24d172b
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