Characteristics of BCR–ABL gene variants in patients of chronic myeloid leukemia

Depending on breakpoints of rearrangement different types of BCR–ABL fusion protein can be generated in patients of chronic myeloid leukemia (CML). The aim of this study is to observe frequencies of major transcripts in CML patients by reverse transcriptase polymerase chain reaction (RT-PCR) and the...

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Autores principales:	Amin Huma, Ahmed Suhaib
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	bcr–abl chronic myelyoid leukemia fusion transcript major breakpoint cluster region reverse transcriptase pcr Medicine R
Acceso en línea:	https://doaj.org/article/506ed547dec04fe48c66cd72fecf7eb5
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id	oai:doaj.org-article:506ed547dec04fe48c66cd72fecf7eb5
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spelling	oai:doaj.org-article:506ed547dec04fe48c66cd72fecf7eb52021-12-05T14:10:54ZCharacteristics of BCR–ABL gene variants in patients of chronic myeloid leukemia2391-546310.1515/med-2021-0309https://doaj.org/article/506ed547dec04fe48c66cd72fecf7eb52021-06-01T00:00:00Zhttps://doi.org/10.1515/med-2021-0309https://doaj.org/toc/2391-5463Depending on breakpoints of rearrangement different types of BCR–ABL fusion protein can be generated in patients of chronic myeloid leukemia (CML). The aim of this study is to observe frequencies of major transcripts in CML patients by reverse transcriptase polymerase chain reaction (RT-PCR) and their hematological features at the time of presentation.Amin HumaAhmed SuhaibDe Gruyterarticlebcr–ablchronic myelyoid leukemiafusion transcriptmajor breakpoint cluster regionreverse transcriptase pcrMedicineRENOpen Medicine, Vol 16, Iss 1, Pp 904-912 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	bcr–abl chronic myelyoid leukemia fusion transcript major breakpoint cluster region reverse transcriptase pcr Medicine R
spellingShingle	bcr–abl chronic myelyoid leukemia fusion transcript major breakpoint cluster region reverse transcriptase pcr Medicine R Amin Huma Ahmed Suhaib Characteristics of BCR–ABL gene variants in patients of chronic myeloid leukemia
description	Depending on breakpoints of rearrangement different types of BCR–ABL fusion protein can be generated in patients of chronic myeloid leukemia (CML). The aim of this study is to observe frequencies of major transcripts in CML patients by reverse transcriptase polymerase chain reaction (RT-PCR) and their hematological features at the time of presentation.
format	article
author	Amin Huma Ahmed Suhaib
author_facet	Amin Huma Ahmed Suhaib
author_sort	Amin Huma
title	Characteristics of BCR–ABL gene variants in patients of chronic myeloid leukemia
title_short	Characteristics of BCR–ABL gene variants in patients of chronic myeloid leukemia
title_full	Characteristics of BCR–ABL gene variants in patients of chronic myeloid leukemia
title_fullStr	Characteristics of BCR–ABL gene variants in patients of chronic myeloid leukemia
title_full_unstemmed	Characteristics of BCR–ABL gene variants in patients of chronic myeloid leukemia
title_sort	characteristics of bcr–abl gene variants in patients of chronic myeloid leukemia
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/506ed547dec04fe48c66cd72fecf7eb5
work_keys_str_mv	AT aminhuma characteristicsofbcrablgenevariantsinpatientsofchronicmyeloidleukemia AT ahmedsuhaib characteristicsofbcrablgenevariantsinpatientsofchronicmyeloidleukemia
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Characteristics of BCR–ABL gene variants in patients of chronic myeloid leukemia

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