Rhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis

ABSTRACT Next-generation sequencing (NGS) has been used to investigate the diversity and maturation of broadly neutralizing antibodies (bNAbs) in HIV-1-infected individuals. However, the application of NGS to the preclinical assessment of human vaccines, particularly the monitoring of vaccine-induce...

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Main Authors: Kaifan Dai, Linling He, Salar N. Khan, Sijy O’Dell, Krisha McKee, Karen Tran, Yuxing Li, Christopher Sundling, Charles D. Morris, John R. Mascola, Gunilla B. Karlsson Hedestam, Richard T. Wyatt, Jiang Zhu
Format: article
Language:EN
Published: American Society for Microbiology 2015
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Online Access:https://doaj.org/article/507b7507aa2149f498faf758163bcd43
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