Rhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis
ABSTRACT Next-generation sequencing (NGS) has been used to investigate the diversity and maturation of broadly neutralizing antibodies (bNAbs) in HIV-1-infected individuals. However, the application of NGS to the preclinical assessment of human vaccines, particularly the monitoring of vaccine-induce...
Guardado en:
Autores principales: | Kaifan Dai, Linling He, Salar N. Khan, Sijy O’Dell, Krisha McKee, Karen Tran, Yuxing Li, Christopher Sundling, Charles D. Morris, John R. Mascola, Gunilla B. Karlsson Hedestam, Richard T. Wyatt, Jiang Zhu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2015
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Materias: | |
Acceso en línea: | https://doaj.org/article/507b7507aa2149f498faf758163bcd43 |
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