Motor-evacuation disturbance of the upper digestive tract as a manifestation of autonomous neuropathyin patients with type 1 diabetes mellitus

AIMS: To elucidate the prevalence of delayed gastroduodenal transit in patients with type 1 diabetes mellitus (DM1) compared with controls havingunaffected carbohydrate metabolism. MATERIALS AND METHODS: The study included 159 DM1 patients and 128 ones with symptoms of dyspepsia and normal carbohyd...

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Autores principales:	Yu. G. Leytes, V. I. Nevmerzhitsky, Inna I. Klefortova
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2009
Materias:	gastroparesis neuropathy autonomous nervous system 13c-caprylic acid breast test motylline erythromycin Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/508dec35d91a4f77b8e4a09070c3503e
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spelling	oai:doaj.org-article:508dec35d91a4f77b8e4a09070c3503e2021-11-14T09:00:13ZMotor-evacuation disturbance of the upper digestive tract as a manifestation of autonomous neuropathyin patients with type 1 diabetes mellitus2072-03512072-037810.14341/2072-0351-5402https://doaj.org/article/508dec35d91a4f77b8e4a09070c3503e2009-06-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5402https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378AIMS: To elucidate the prevalence of delayed gastroduodenal transit in patients with type 1 diabetes mellitus (DM1) compared with controls havingunaffected carbohydrate metabolism. MATERIALS AND METHODS: The study included 159 DM1 patients and 128 ones with symptoms of dyspepsia and normal carbohydrate metabolism. The presenceof food remains in the stomach after the 12-hour fast (detected by oesophagogastroduodenoscopy) was regarded as a delay of gastroduodenal transit. RESULTS: In a group of DM1 patients, 13.70% of the cases had endoscopically confirmed delay of food evacuation from the stomach. No signs of gastroparesiswere documented in the control group. CONCLUSIONS: Certain patients with DM1 suffer a marked impairment of gastroduodenal transit (13.7% of the cases in the present study). This disorderaffects the time of onset of carbohydrate absorption. Therefore, such patients need their mealtimes to be chosen on an individual basis.Yu. G. LeytesV. I. NevmerzhitskyInna I. KlefortovaEndocrinology Research Centrearticlegastroparesisneuropathyautonomous nervous system13c-caprylic acidbreast testmotyllineerythromycinNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 12, Iss 2, Pp 68-71 (2009)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	gastroparesis neuropathy autonomous nervous system 13c-caprylic acid breast test motylline erythromycin Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	gastroparesis neuropathy autonomous nervous system 13c-caprylic acid breast test motylline erythromycin Nutritional diseases. Deficiency diseases RC620-627 Yu. G. Leytes V. I. Nevmerzhitsky Inna I. Klefortova Motor-evacuation disturbance of the upper digestive tract as a manifestation of autonomous neuropathyin patients with type 1 diabetes mellitus
description	AIMS: To elucidate the prevalence of delayed gastroduodenal transit in patients with type 1 diabetes mellitus (DM1) compared with controls havingunaffected carbohydrate metabolism. MATERIALS AND METHODS: The study included 159 DM1 patients and 128 ones with symptoms of dyspepsia and normal carbohydrate metabolism. The presenceof food remains in the stomach after the 12-hour fast (detected by oesophagogastroduodenoscopy) was regarded as a delay of gastroduodenal transit. RESULTS: In a group of DM1 patients, 13.70% of the cases had endoscopically confirmed delay of food evacuation from the stomach. No signs of gastroparesiswere documented in the control group. CONCLUSIONS: Certain patients with DM1 suffer a marked impairment of gastroduodenal transit (13.7% of the cases in the present study). This disorderaffects the time of onset of carbohydrate absorption. Therefore, such patients need their mealtimes to be chosen on an individual basis.
format	article
author	Yu. G. Leytes V. I. Nevmerzhitsky Inna I. Klefortova
author_facet	Yu. G. Leytes V. I. Nevmerzhitsky Inna I. Klefortova
author_sort	Yu. G. Leytes
title	Motor-evacuation disturbance of the upper digestive tract as a manifestation of autonomous neuropathyin patients with type 1 diabetes mellitus
title_short	Motor-evacuation disturbance of the upper digestive tract as a manifestation of autonomous neuropathyin patients with type 1 diabetes mellitus
title_full	Motor-evacuation disturbance of the upper digestive tract as a manifestation of autonomous neuropathyin patients with type 1 diabetes mellitus
title_fullStr	Motor-evacuation disturbance of the upper digestive tract as a manifestation of autonomous neuropathyin patients with type 1 diabetes mellitus
title_full_unstemmed	Motor-evacuation disturbance of the upper digestive tract as a manifestation of autonomous neuropathyin patients with type 1 diabetes mellitus
title_sort	motor-evacuation disturbance of the upper digestive tract as a manifestation of autonomous neuropathyin patients with type 1 diabetes mellitus
publisher	Endocrinology Research Centre
publishDate	2009
url	https://doaj.org/article/508dec35d91a4f77b8e4a09070c3503e
work_keys_str_mv	AT yugleytes motorevacuationdisturbanceoftheupperdigestivetractasamanifestationofautonomousneuropathyinpatientswithtype1diabetesmellitus AT vinevmerzhitsky motorevacuationdisturbanceoftheupperdigestivetractasamanifestationofautonomousneuropathyinpatientswithtype1diabetesmellitus AT innaiklefortova motorevacuationdisturbanceoftheupperdigestivetractasamanifestationofautonomousneuropathyinpatientswithtype1diabetesmellitus
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Motor-evacuation disturbance of the upper digestive tract as a manifestation of autonomous neuropathyin patients with type 1 diabetes mellitus

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