SCOP/PHLPP1β mediates circadian regulation of long-term recognition memory

SCOP/PHLPP1β mediates circadian regulation of long-term recognition memory

Learning and memory are subject to circadian variation, though the molecular mechanisms behind this are unclear. Here, the authors show SCOP, a regulator of hippocampal memory, undergoes circadian changes in CA1 membrane raft dynamics and contributes to time-dependent changes in long-term memory.

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Autores principales: Kimiko Shimizu, Yodai Kobayashi, Erika Nakatsuji, Maya Yamazaki, Shigeki Shimba, Kenji Sakimura, Yoshitaka Fukada
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/508e19412e674a189f1324a0c8aabd5b
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spelling oai:doaj.org-article:508e19412e674a189f1324a0c8aabd5b2021-12-02T16:49:56ZSCOP/PHLPP1β mediates circadian regulation of long-term recognition memory10.1038/ncomms129262041-1723https://doaj.org/article/508e19412e674a189f1324a0c8aabd5b2016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12926https://doaj.org/toc/2041-1723Learning and memory are subject to circadian variation, though the molecular mechanisms behind this are unclear. Here, the authors show SCOP, a regulator of hippocampal memory, undergoes circadian changes in CA1 membrane raft dynamics and contributes to time-dependent changes in long-term memory.Kimiko ShimizuYodai KobayashiErika NakatsujiMaya YamazakiShigeki ShimbaKenji SakimuraYoshitaka FukadaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kimiko Shimizu
Yodai Kobayashi
Erika Nakatsuji
Maya Yamazaki
Shigeki Shimba
Kenji Sakimura
Yoshitaka Fukada
SCOP/PHLPP1β mediates circadian regulation of long-term recognition memory
description Learning and memory are subject to circadian variation, though the molecular mechanisms behind this are unclear. Here, the authors show SCOP, a regulator of hippocampal memory, undergoes circadian changes in CA1 membrane raft dynamics and contributes to time-dependent changes in long-term memory.
format article
author Kimiko Shimizu
Yodai Kobayashi
Erika Nakatsuji
Maya Yamazaki
Shigeki Shimba
Kenji Sakimura
Yoshitaka Fukada
author_facet Kimiko Shimizu
Yodai Kobayashi
Erika Nakatsuji
Maya Yamazaki
Shigeki Shimba
Kenji Sakimura
Yoshitaka Fukada
author_sort Kimiko Shimizu
title SCOP/PHLPP1β mediates circadian regulation of long-term recognition memory
title_short SCOP/PHLPP1β mediates circadian regulation of long-term recognition memory
title_full SCOP/PHLPP1β mediates circadian regulation of long-term recognition memory
title_fullStr SCOP/PHLPP1β mediates circadian regulation of long-term recognition memory
title_full_unstemmed SCOP/PHLPP1β mediates circadian regulation of long-term recognition memory
title_sort scop/phlpp1β mediates circadian regulation of long-term recognition memory
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/508e19412e674a189f1324a0c8aabd5b
work_keys_str_mv AT kimikoshimizu scopphlpp1bmediatescircadianregulationoflongtermrecognitionmemory
AT yodaikobayashi scopphlpp1bmediatescircadianregulationoflongtermrecognitionmemory
AT erikanakatsuji scopphlpp1bmediatescircadianregulationoflongtermrecognitionmemory
AT mayayamazaki scopphlpp1bmediatescircadianregulationoflongtermrecognitionmemory
AT shigekishimba scopphlpp1bmediatescircadianregulationoflongtermrecognitionmemory
AT kenjisakimura scopphlpp1bmediatescircadianregulationoflongtermrecognitionmemory
AT yoshitakafukada scopphlpp1bmediatescircadianregulationoflongtermrecognitionmemory
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