Pathological Impact of Johne’s disease in Cattle: A Review Article

Johne’s disease is an international healthiness problem affecting ruminants. It is caused by Myobacterium avium spp. paratuberculosis (MAP). It has serious production-limiting important and also caused significant cost-effective loss in flocks due to direct impact on delayed/reduced breeding, infer...

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Autores principales:	S.A. Radam, I.B. Falih, S.L. Hassan, H.B. AL-Sabaawy
Formato:	article
Lenguaje:	EN
Publicado:	Egyptian Society for Animal Management 2021
Materias:	cattle giant cells granuloma johne’s disease paratuberculosis Zoology QL1-991 Veterinary medicine SF600-1100 Animal biochemistry QP501-801
Acceso en línea:	https://dx.doi.org/10.21608/javs.2021.76316.1080 https://doaj.org/article/509eae4e0e824f48a51e7d9c8ad26671
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spelling	oai:doaj.org-article:509eae4e0e824f48a51e7d9c8ad266712021-12-02T16:10:10ZPathological Impact of Johne’s disease in Cattle: A Review Articlehttps://dx.doi.org/10.21608/javs.2021.76316.10801687-40722090-3308https://doaj.org/article/509eae4e0e824f48a51e7d9c8ad266712021-07-01T00:00:00Zhttps://javs.journals.ekb.eg/article_179295.htmlhttps://doaj.org/toc/1687-4072https://doaj.org/toc/2090-3308Johne’s disease is an international healthiness problem affecting ruminants. It is caused by Myobacterium avium spp. paratuberculosis (MAP). It has serious production-limiting important and also caused significant cost-effective loss in flocks due to direct impact on delayed/reduced breeding, infertility, culling, mortality, and milk reduction. This disease is problematic to diagnose because of elongated incubation times. Proof of identity this disease subclinical can shed the organism as a source of infection for other herds; so, it is critical for control. The present study deals with the morphological (grossly, histopathologically and histochemically) characterization of the disease in cattle. The corpse appears hidebound with sunken eyes and with persistent and non- responsive diarrhea. The necropsy of visceral showed gelatinization and outlying fat. Grossly chiefly pathological alterations in digestive tract such as severe congested of small intestine with marked thickening of its wall a combined with enlargement of mesenteric lymph nodes and gallbladder appear distension with severe thickening walls and blood mixed with bile. Histopathological examinations revealed severe infiltrations of inflammatory cells such as macrophages, lymphocytes, and epithelioid cells with multiple langhans giant cells in bowel layers and mesenteric lymph nodes with diffuse lepromatous reaction were observed in these lymph nodes and other organs like liver, tonsils and kidney. S.A. RadamI.B. FalihS.L. HassanH.B. AL-SabaawyEgyptian Society for Animal Managementarticlecattlegiant cellsgranulomajohne’s diseaseparatuberculosisZoologyQL1-991Veterinary medicineSF600-1100Animal biochemistryQP501-801ENJournal of Applied Veterinary Sciences, Vol 6, Iss 3, Pp 38-47 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cattle giant cells granuloma johne’s disease paratuberculosis Zoology QL1-991 Veterinary medicine SF600-1100 Animal biochemistry QP501-801
spellingShingle	cattle giant cells granuloma johne’s disease paratuberculosis Zoology QL1-991 Veterinary medicine SF600-1100 Animal biochemistry QP501-801 S.A. Radam I.B. Falih S.L. Hassan H.B. AL-Sabaawy Pathological Impact of Johne’s disease in Cattle: A Review Article
description	Johne’s disease is an international healthiness problem affecting ruminants. It is caused by Myobacterium avium spp. paratuberculosis (MAP). It has serious production-limiting important and also caused significant cost-effective loss in flocks due to direct impact on delayed/reduced breeding, infertility, culling, mortality, and milk reduction. This disease is problematic to diagnose because of elongated incubation times. Proof of identity this disease subclinical can shed the organism as a source of infection for other herds; so, it is critical for control. The present study deals with the morphological (grossly, histopathologically and histochemically) characterization of the disease in cattle. The corpse appears hidebound with sunken eyes and with persistent and non- responsive diarrhea. The necropsy of visceral showed gelatinization and outlying fat. Grossly chiefly pathological alterations in digestive tract such as severe congested of small intestine with marked thickening of its wall a combined with enlargement of mesenteric lymph nodes and gallbladder appear distension with severe thickening walls and blood mixed with bile. Histopathological examinations revealed severe infiltrations of inflammatory cells such as macrophages, lymphocytes, and epithelioid cells with multiple langhans giant cells in bowel layers and mesenteric lymph nodes with diffuse lepromatous reaction were observed in these lymph nodes and other organs like liver, tonsils and kidney.
format	article
author	S.A. Radam I.B. Falih S.L. Hassan H.B. AL-Sabaawy
author_facet	S.A. Radam I.B. Falih S.L. Hassan H.B. AL-Sabaawy
author_sort	S.A. Radam
title	Pathological Impact of Johne’s disease in Cattle: A Review Article
title_short	Pathological Impact of Johne’s disease in Cattle: A Review Article
title_full	Pathological Impact of Johne’s disease in Cattle: A Review Article
title_fullStr	Pathological Impact of Johne’s disease in Cattle: A Review Article
title_full_unstemmed	Pathological Impact of Johne’s disease in Cattle: A Review Article
title_sort	pathological impact of johne’s disease in cattle: a review article
publisher	Egyptian Society for Animal Management
publishDate	2021
url	https://dx.doi.org/10.21608/javs.2021.76316.1080 https://doaj.org/article/509eae4e0e824f48a51e7d9c8ad26671
work_keys_str_mv	AT saradam pathologicalimpactofjohnesdiseaseincattleareviewarticle AT ibfalih pathologicalimpactofjohnesdiseaseincattleareviewarticle AT slhassan pathologicalimpactofjohnesdiseaseincattleareviewarticle AT hbalsabaawy pathologicalimpactofjohnesdiseaseincattleareviewarticle
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Pathological Impact of Johne’s disease in Cattle: A Review Article

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