Diffuse unilateral subacute neuroretinitis in a young boy: a case report

FNg Guan-Fook, Abd Aziz Hayati, Mohd Noor Raja-Azmi, Ahmad Tajudin Liza-Sharmini, Wan Hitam Wan-Hazabbah, Embong ZunainaDepartment of Ophthalmology, School of Medical Science, Universiti Sains Malaysia, Kubang Kerian, Kelantan, MalaysiaAbstract: We report a case of diffuse unilateral subacute neuror...

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Autores principales:	Guan-Fook N, Hayati AA, Raja-Azmi MN, Liza-Sharmini AT, Wan-Hazabbah WH, Zunaina E
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/50ae195cba494fdb9eed0a0cc3e6ed80
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spelling	oai:doaj.org-article:50ae195cba494fdb9eed0a0cc3e6ed802021-12-02T00:23:28ZDiffuse unilateral subacute neuroretinitis in a young boy: a case report1177-54671177-5483https://doaj.org/article/50ae195cba494fdb9eed0a0cc3e6ed802012-03-01T00:00:00Zhttp://www.dovepress.com/diffuse-unilateral-subacute-neuroretinitis-in-a-young-boy-a-case-repor-a9581https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483FNg Guan-Fook, Abd Aziz Hayati, Mohd Noor Raja-Azmi, Ahmad Tajudin Liza-Sharmini, Wan Hitam Wan-Hazabbah, Embong ZunainaDepartment of Ophthalmology, School of Medical Science, Universiti Sains Malaysia, Kubang Kerian, Kelantan, MalaysiaAbstract: We report a case of diffuse unilateral subacute neuroretinitis in a young boy with no clinical visualization of nematode. The diagnosis was made based on clinical findings and detection of Toxocara immunoglobulin G by Western blot test. An 11-year-old Malay boy presented with progressive blurring of vision in the left eye for a duration of 1 year. It was associated with intermittent floaters. Visual acuity in the left eye was 6/45 and improved to 6/24 with pinhole. There was positive relative afferent pupillary defect, impaired color vision, and presence of red desaturation in the left eye. There were occasional cells in the anterior chamber with no conjunctiva injection. Posterior segment examination revealed mild-to-moderate vitritis and generalized pigmentary changes of the retina with attenuated vessels. The optic disk was slightly hyperemic with mild edema. There was presence of multiple, focal, gray-white subretinal lesions at the inferior part of the retina. Full blood picture results showed eosinophilia with detection of Toxocara immunoglobulin G by Western blot test. Investigations for other infective causes and connective tissue diseases were negative. The diagnosis of diffuse unilateral subacute neuroretinitis secondary to Toxocara was made based on clinical findings and laboratory results. He was treated with oral albendazole 400 mg daily for 5 days and oral prednisolone 1 mg/kg with tapering doses over 6 weeks. At 1 month follow-up, the inflammation had reduced, and multiple, focal, gray-white subretinal lesions were resolved; however there was no improvement of vision.Keywords: diffuse unilateral subacute neuroretinitis, Toxocara IgG, albendazoleGuan-Fook NHayati AARaja-Azmi MNLiza-Sharmini ATWan-Hazabbah WHZunaina EDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 487-490 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Guan-Fook N Hayati AA Raja-Azmi MN Liza-Sharmini AT Wan-Hazabbah WH Zunaina E Diffuse unilateral subacute neuroretinitis in a young boy: a case report
description	FNg Guan-Fook, Abd Aziz Hayati, Mohd Noor Raja-Azmi, Ahmad Tajudin Liza-Sharmini, Wan Hitam Wan-Hazabbah, Embong ZunainaDepartment of Ophthalmology, School of Medical Science, Universiti Sains Malaysia, Kubang Kerian, Kelantan, MalaysiaAbstract: We report a case of diffuse unilateral subacute neuroretinitis in a young boy with no clinical visualization of nematode. The diagnosis was made based on clinical findings and detection of Toxocara immunoglobulin G by Western blot test. An 11-year-old Malay boy presented with progressive blurring of vision in the left eye for a duration of 1 year. It was associated with intermittent floaters. Visual acuity in the left eye was 6/45 and improved to 6/24 with pinhole. There was positive relative afferent pupillary defect, impaired color vision, and presence of red desaturation in the left eye. There were occasional cells in the anterior chamber with no conjunctiva injection. Posterior segment examination revealed mild-to-moderate vitritis and generalized pigmentary changes of the retina with attenuated vessels. The optic disk was slightly hyperemic with mild edema. There was presence of multiple, focal, gray-white subretinal lesions at the inferior part of the retina. Full blood picture results showed eosinophilia with detection of Toxocara immunoglobulin G by Western blot test. Investigations for other infective causes and connective tissue diseases were negative. The diagnosis of diffuse unilateral subacute neuroretinitis secondary to Toxocara was made based on clinical findings and laboratory results. He was treated with oral albendazole 400 mg daily for 5 days and oral prednisolone 1 mg/kg with tapering doses over 6 weeks. At 1 month follow-up, the inflammation had reduced, and multiple, focal, gray-white subretinal lesions were resolved; however there was no improvement of vision.Keywords: diffuse unilateral subacute neuroretinitis, Toxocara IgG, albendazole
format	article
author	Guan-Fook N Hayati AA Raja-Azmi MN Liza-Sharmini AT Wan-Hazabbah WH Zunaina E
author_facet	Guan-Fook N Hayati AA Raja-Azmi MN Liza-Sharmini AT Wan-Hazabbah WH Zunaina E
author_sort	Guan-Fook N
title	Diffuse unilateral subacute neuroretinitis in a young boy: a case report
title_short	Diffuse unilateral subacute neuroretinitis in a young boy: a case report
title_full	Diffuse unilateral subacute neuroretinitis in a young boy: a case report
title_fullStr	Diffuse unilateral subacute neuroretinitis in a young boy: a case report
title_full_unstemmed	Diffuse unilateral subacute neuroretinitis in a young boy: a case report
title_sort	diffuse unilateral subacute neuroretinitis in a young boy: a case report
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/50ae195cba494fdb9eed0a0cc3e6ed80
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Diffuse unilateral subacute neuroretinitis in a young boy: a case report

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