Wnt-PLC-IP3-Connexin-Ca2+ axis maintains ependymal motile cilia in zebrafish spinal cord
Ependymal cells are supporting cells in the central nervous system. Here the authors elucidate a signalling axis in zebrafish spinal cord ependymal cells that is important for motile cilia assembly and maintenance, demonstrating that it depends on intercellular propagation of calcium ions via connex...
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2020
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/50b03acaa0d0416f90bb32ff426f7eea |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:50b03acaa0d0416f90bb32ff426f7eea |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:50b03acaa0d0416f90bb32ff426f7eea2021-12-02T16:50:04ZWnt-PLC-IP3-Connexin-Ca2+ axis maintains ependymal motile cilia in zebrafish spinal cord10.1038/s41467-020-15248-22041-1723https://doaj.org/article/50b03acaa0d0416f90bb32ff426f7eea2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15248-2https://doaj.org/toc/2041-1723Ependymal cells are supporting cells in the central nervous system. Here the authors elucidate a signalling axis in zebrafish spinal cord ependymal cells that is important for motile cilia assembly and maintenance, demonstrating that it depends on intercellular propagation of calcium ions via connexin 43.Jun ZhangGopalakrishnan ChandrasekaranWenting LiDong-Young KimIn Young JeongSo-Hyun LeeTing LiangJin Young BaeIsaac ChoiHyuno KangJin-Soo MaengMyeong-Kyu KimTaewon LeeSeung Woo ParkMin Jung KimHyung-Seok KimHyunju RoYong Chul BaeHae-Chul ParkEun Young ChoiSeok-Yong ChoiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Jun Zhang Gopalakrishnan Chandrasekaran Wenting Li Dong-Young Kim In Young Jeong So-Hyun Lee Ting Liang Jin Young Bae Isaac Choi Hyuno Kang Jin-Soo Maeng Myeong-Kyu Kim Taewon Lee Seung Woo Park Min Jung Kim Hyung-Seok Kim Hyunju Ro Yong Chul Bae Hae-Chul Park Eun Young Choi Seok-Yong Choi Wnt-PLC-IP3-Connexin-Ca2+ axis maintains ependymal motile cilia in zebrafish spinal cord |
| description |
Ependymal cells are supporting cells in the central nervous system. Here the authors elucidate a signalling axis in zebrafish spinal cord ependymal cells that is important for motile cilia assembly and maintenance, demonstrating that it depends on intercellular propagation of calcium ions via connexin 43. |
| format |
article |
| author |
Jun Zhang Gopalakrishnan Chandrasekaran Wenting Li Dong-Young Kim In Young Jeong So-Hyun Lee Ting Liang Jin Young Bae Isaac Choi Hyuno Kang Jin-Soo Maeng Myeong-Kyu Kim Taewon Lee Seung Woo Park Min Jung Kim Hyung-Seok Kim Hyunju Ro Yong Chul Bae Hae-Chul Park Eun Young Choi Seok-Yong Choi |
| author_facet |
Jun Zhang Gopalakrishnan Chandrasekaran Wenting Li Dong-Young Kim In Young Jeong So-Hyun Lee Ting Liang Jin Young Bae Isaac Choi Hyuno Kang Jin-Soo Maeng Myeong-Kyu Kim Taewon Lee Seung Woo Park Min Jung Kim Hyung-Seok Kim Hyunju Ro Yong Chul Bae Hae-Chul Park Eun Young Choi Seok-Yong Choi |
| author_sort |
Jun Zhang |
| title |
Wnt-PLC-IP3-Connexin-Ca2+ axis maintains ependymal motile cilia in zebrafish spinal cord |
| title_short |
Wnt-PLC-IP3-Connexin-Ca2+ axis maintains ependymal motile cilia in zebrafish spinal cord |
| title_full |
Wnt-PLC-IP3-Connexin-Ca2+ axis maintains ependymal motile cilia in zebrafish spinal cord |
| title_fullStr |
Wnt-PLC-IP3-Connexin-Ca2+ axis maintains ependymal motile cilia in zebrafish spinal cord |
| title_full_unstemmed |
Wnt-PLC-IP3-Connexin-Ca2+ axis maintains ependymal motile cilia in zebrafish spinal cord |
| title_sort |
wnt-plc-ip3-connexin-ca2+ axis maintains ependymal motile cilia in zebrafish spinal cord |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/50b03acaa0d0416f90bb32ff426f7eea |
| work_keys_str_mv |
AT junzhang wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT gopalakrishnanchandrasekaran wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT wentingli wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT dongyoungkim wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT inyoungjeong wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT sohyunlee wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT tingliang wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT jinyoungbae wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT isaacchoi wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT hyunokang wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT jinsoomaeng wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT myeongkyukim wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT taewonlee wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT seungwoopark wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT minjungkim wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT hyungseokkim wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT hyunjuro wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT yongchulbae wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT haechulpark wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT eunyoungchoi wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord AT seokyongchoi wntplcip3connexinca2axismaintainsependymalmotileciliainzebrafishspinalcord |
| _version_ |
1718383097771196416 |