Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment

The use of CSF for diagnosis of metastatic brain tumors could be of clinical and patient benefit. Here the authors undertake a single-cell RNA analysis of CSF and brain to determine whether the phenotype in the CSF is reflective of the phenotype in the tumor.

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Autores principales:	Carlota Rubio-Perez, Ester Planas-Rigol, Juan L. Trincado, Ester Bonfill-Teixidor, Alexandra Arias, Domenica Marchese, Catia Moutinho, Garazi Serna, Leire Pedrosa, Raffaella Iurlaro, Francisco Martínez-Ricarte, Laura Escudero, Esteban Cordero, Marta Cicuendez, Sara Ruiz, Genís Parra, Paolo Nuciforo, Josep Gonzalez, Estela Pineda, Juan Sahuquillo, Josep Tabernero, Holger Heyn, Joan Seoane
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/50b186a5ef3f4b8e915baf48cb69dbc4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:50b186a5ef3f4b8e915baf48cb69dbc42021-12-02T13:34:44ZImmune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment10.1038/s41467-021-21789-x2041-1723https://doaj.org/article/50b186a5ef3f4b8e915baf48cb69dbc42021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21789-xhttps://doaj.org/toc/2041-1723The use of CSF for diagnosis of metastatic brain tumors could be of clinical and patient benefit. Here the authors undertake a single-cell RNA analysis of CSF and brain to determine whether the phenotype in the CSF is reflective of the phenotype in the tumor.Carlota Rubio-PerezEster Planas-RigolJuan L. TrincadoEster Bonfill-TeixidorAlexandra AriasDomenica MarcheseCatia MoutinhoGarazi SernaLeire PedrosaRaffaella IurlaroFrancisco Martínez-RicarteLaura EscuderoEsteban CorderoMarta CicuendezSara RuizGenís ParraPaolo NuciforoJosep GonzalezEstela PinedaJuan SahuquilloJosep TaberneroHolger HeynJoan SeoaneNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Carlota Rubio-Perez Ester Planas-Rigol Juan L. Trincado Ester Bonfill-Teixidor Alexandra Arias Domenica Marchese Catia Moutinho Garazi Serna Leire Pedrosa Raffaella Iurlaro Francisco Martínez-Ricarte Laura Escudero Esteban Cordero Marta Cicuendez Sara Ruiz Genís Parra Paolo Nuciforo Josep Gonzalez Estela Pineda Juan Sahuquillo Josep Tabernero Holger Heyn Joan Seoane Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment
description	The use of CSF for diagnosis of metastatic brain tumors could be of clinical and patient benefit. Here the authors undertake a single-cell RNA analysis of CSF and brain to determine whether the phenotype in the CSF is reflective of the phenotype in the tumor.
format	article
author	Carlota Rubio-Perez Ester Planas-Rigol Juan L. Trincado Ester Bonfill-Teixidor Alexandra Arias Domenica Marchese Catia Moutinho Garazi Serna Leire Pedrosa Raffaella Iurlaro Francisco Martínez-Ricarte Laura Escudero Esteban Cordero Marta Cicuendez Sara Ruiz Genís Parra Paolo Nuciforo Josep Gonzalez Estela Pineda Juan Sahuquillo Josep Tabernero Holger Heyn Joan Seoane
author_facet	Carlota Rubio-Perez Ester Planas-Rigol Juan L. Trincado Ester Bonfill-Teixidor Alexandra Arias Domenica Marchese Catia Moutinho Garazi Serna Leire Pedrosa Raffaella Iurlaro Francisco Martínez-Ricarte Laura Escudero Esteban Cordero Marta Cicuendez Sara Ruiz Genís Parra Paolo Nuciforo Josep Gonzalez Estela Pineda Juan Sahuquillo Josep Tabernero Holger Heyn Joan Seoane
author_sort	Carlota Rubio-Perez
title	Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment
title_short	Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment
title_full	Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment
title_fullStr	Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment
title_full_unstemmed	Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment
title_sort	immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/50b186a5ef3f4b8e915baf48cb69dbc4
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Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment

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