Oxidative Stress Leads to β-Cell Dysfunction Through Loss of β-Cell Identity

Pancreatic β-cell failure is a critical event in the onset of both main types of diabetes mellitus but underlying mechanisms are not fully understood. β-cells have low anti-oxidant capacity, making them more susceptible to oxidative stress. In type 1 diabetes (T1D), reactive oxygen species (ROS) are...

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Autores principales:	Floris Leenders, Nathalie Groen, Natascha de Graaf, Marten A. Engelse, Ton J. Rabelink, Eelco J. P. de Koning, Françoise Carlotti
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	oxidative stress beta-cell dysfunction beta-cell identity beta-cell dedifferentiation type 1 diabetes mellitus (T1D) Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/50b393711df249ed8ab6d9d9ee96364a
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Oxidative Stress Leads to β-Cell Dysfunction Through Loss of β-Cell Identity

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