Structural basis for Fullerene geometry in a human endogenous retrovirus capsid

In retroviruses, the capsid protein (CA) forms a shell surrounding the viral core. Here the authors combine cryo-electron microscopy with NMR and X-ray crystallography to examine the CA structure from the human endogenous retrovirus HML2 (HERV-K) and determine the structures of four Fullerene CA clo...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Oliver Acton, Tim Grant, Giuseppe Nicastro, Neil J. Ball, David C. Goldstone, Laura E. Robertson, Kasim Sader, Andrea Nans, Andres Ramos, Jonathan P. Stoye, Ian A. Taylor, Peter B. Rosenthal
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/50d5434d21c24069a587937d07c9ffa6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:50d5434d21c24069a587937d07c9ffa6
record_format	dspace
spelling	oai:doaj.org-article:50d5434d21c24069a587937d07c9ffa62021-12-02T17:01:32ZStructural basis for Fullerene geometry in a human endogenous retrovirus capsid10.1038/s41467-019-13786-y2041-1723https://doaj.org/article/50d5434d21c24069a587937d07c9ffa62019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13786-yhttps://doaj.org/toc/2041-1723In retroviruses, the capsid protein (CA) forms a shell surrounding the viral core. Here the authors combine cryo-electron microscopy with NMR and X-ray crystallography to examine the CA structure from the human endogenous retrovirus HML2 (HERV-K) and determine the structures of four Fullerene CA closed shells that reveal the molecular basis of capsid assembly.Oliver ActonTim GrantGiuseppe NicastroNeil J. BallDavid C. GoldstoneLaura E. RobertsonKasim SaderAndrea NansAndres RamosJonathan P. StoyeIan A. TaylorPeter B. RosenthalNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Oliver Acton Tim Grant Giuseppe Nicastro Neil J. Ball David C. Goldstone Laura E. Robertson Kasim Sader Andrea Nans Andres Ramos Jonathan P. Stoye Ian A. Taylor Peter B. Rosenthal Structural basis for Fullerene geometry in a human endogenous retrovirus capsid
description	In retroviruses, the capsid protein (CA) forms a shell surrounding the viral core. Here the authors combine cryo-electron microscopy with NMR and X-ray crystallography to examine the CA structure from the human endogenous retrovirus HML2 (HERV-K) and determine the structures of four Fullerene CA closed shells that reveal the molecular basis of capsid assembly.
format	article
author	Oliver Acton Tim Grant Giuseppe Nicastro Neil J. Ball David C. Goldstone Laura E. Robertson Kasim Sader Andrea Nans Andres Ramos Jonathan P. Stoye Ian A. Taylor Peter B. Rosenthal
author_facet	Oliver Acton Tim Grant Giuseppe Nicastro Neil J. Ball David C. Goldstone Laura E. Robertson Kasim Sader Andrea Nans Andres Ramos Jonathan P. Stoye Ian A. Taylor Peter B. Rosenthal
author_sort	Oliver Acton
title	Structural basis for Fullerene geometry in a human endogenous retrovirus capsid
title_short	Structural basis for Fullerene geometry in a human endogenous retrovirus capsid
title_full	Structural basis for Fullerene geometry in a human endogenous retrovirus capsid
title_fullStr	Structural basis for Fullerene geometry in a human endogenous retrovirus capsid
title_full_unstemmed	Structural basis for Fullerene geometry in a human endogenous retrovirus capsid
title_sort	structural basis for fullerene geometry in a human endogenous retrovirus capsid
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/50d5434d21c24069a587937d07c9ffa6
work_keys_str_mv	AT oliveracton structuralbasisforfullerenegeometryinahumanendogenousretroviruscapsid AT timgrant structuralbasisforfullerenegeometryinahumanendogenousretroviruscapsid AT giuseppenicastro structuralbasisforfullerenegeometryinahumanendogenousretroviruscapsid AT neiljball structuralbasisforfullerenegeometryinahumanendogenousretroviruscapsid AT davidcgoldstone structuralbasisforfullerenegeometryinahumanendogenousretroviruscapsid AT lauraerobertson structuralbasisforfullerenegeometryinahumanendogenousretroviruscapsid AT kasimsader structuralbasisforfullerenegeometryinahumanendogenousretroviruscapsid AT andreanans structuralbasisforfullerenegeometryinahumanendogenousretroviruscapsid AT andresramos structuralbasisforfullerenegeometryinahumanendogenousretroviruscapsid AT jonathanpstoye structuralbasisforfullerenegeometryinahumanendogenousretroviruscapsid AT ianataylor structuralbasisforfullerenegeometryinahumanendogenousretroviruscapsid AT peterbrosenthal structuralbasisforfullerenegeometryinahumanendogenousretroviruscapsid
_version_	1718382081607729152

Structural basis for Fullerene geometry in a human endogenous retrovirus capsid

Ejemplares similares