A cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis

Saponins such as glycyrrhizin, a natural sweetener found in licorice root, are a class of triterpenoids synthesized that are characterized by a glucoronic acid moiety at the C-3 position. Here the authors show that saponin glucuronosylation is catalyzed by cellulose-synthase like enzymes and reconst...

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Autores principales:	Soo Yeon Chung, Hikaru Seki, Yukiko Fujisawa, Yoshikazu Shimoda, Susumu Hiraga, Yuhta Nomura, Kazuki Saito, Masao Ishimoto, Toshiya Muranaka
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/50da0353228b47459b770b0681f56728
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id	oai:doaj.org-article:50da0353228b47459b770b0681f56728
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spelling	oai:doaj.org-article:50da0353228b47459b770b0681f567282021-12-02T14:42:13ZA cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis10.1038/s41467-020-19399-02041-1723https://doaj.org/article/50da0353228b47459b770b0681f567282020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19399-0https://doaj.org/toc/2041-1723Saponins such as glycyrrhizin, a natural sweetener found in licorice root, are a class of triterpenoids synthesized that are characterized by a glucoronic acid moiety at the C-3 position. Here the authors show that saponin glucuronosylation is catalyzed by cellulose-synthase like enzymes and reconstitute glycyrrhizin synthesisin yeast.Soo Yeon ChungHikaru SekiYukiko FujisawaYoshikazu ShimodaSusumu HiragaYuhta NomuraKazuki SaitoMasao IshimotoToshiya MuranakaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Soo Yeon Chung Hikaru Seki Yukiko Fujisawa Yoshikazu Shimoda Susumu Hiraga Yuhta Nomura Kazuki Saito Masao Ishimoto Toshiya Muranaka A cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis
description	Saponins such as glycyrrhizin, a natural sweetener found in licorice root, are a class of triterpenoids synthesized that are characterized by a glucoronic acid moiety at the C-3 position. Here the authors show that saponin glucuronosylation is catalyzed by cellulose-synthase like enzymes and reconstitute glycyrrhizin synthesisin yeast.
format	article
author	Soo Yeon Chung Hikaru Seki Yukiko Fujisawa Yoshikazu Shimoda Susumu Hiraga Yuhta Nomura Kazuki Saito Masao Ishimoto Toshiya Muranaka
author_facet	Soo Yeon Chung Hikaru Seki Yukiko Fujisawa Yoshikazu Shimoda Susumu Hiraga Yuhta Nomura Kazuki Saito Masao Ishimoto Toshiya Muranaka
author_sort	Soo Yeon Chung
title	A cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis
title_short	A cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis
title_full	A cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis
title_fullStr	A cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis
title_full_unstemmed	A cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis
title_sort	cellulose synthase-derived enzyme catalyses 3-o-glucuronosylation in saponin biosynthesis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/50da0353228b47459b770b0681f56728
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A cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis

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