Brca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesis.
Epidemiological studies have shown that one of the strongest risk factors for prostate cancer is a family history of the disease, suggesting that inherited factors play a major role in prostate cancer susceptibility. Germline mutations in BRCA2 predispose to breast and ovarian cancer with its predom...
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Autores principales: | Jeffrey C Francis, Afshan McCarthy, Martin K Thomsen, Alan Ashworth, Amanda Swain |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
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Materias: | |
Acceso en línea: | https://doaj.org/article/50e576c66c604d56ad9f0758ee5b1737 |
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