Ets transcription factor GABP controls T cell homeostasis and immunity

T cells need to undergo rapid proliferation in response to antigenic stimulation. Here the authors show that the Ets family transcription factor GABP is required for T-cell homeostasis and response to infection by inducing Mcm3 and Mcm5 expression and enabling S-phase entry.

Guardado en:

Detalles Bibliográficos
Autores principales:	Chong T. Luo, Hatice U. Osmanbeyoglu, Mytrang H. Do, Michael R. Bivona, Ahmed Toure, Davina Kang, Yuchen Xie, Christina S. Leslie, Ming O. Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/50e6f5509f404eff9801e85bc16331be
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:50e6f5509f404eff9801e85bc16331be
record_format	dspace
spelling	oai:doaj.org-article:50e6f5509f404eff9801e85bc16331be2021-12-02T17:01:16ZEts transcription factor GABP controls T cell homeostasis and immunity10.1038/s41467-017-01020-62041-1723https://doaj.org/article/50e6f5509f404eff9801e85bc16331be2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01020-6https://doaj.org/toc/2041-1723T cells need to undergo rapid proliferation in response to antigenic stimulation. Here the authors show that the Ets family transcription factor GABP is required for T-cell homeostasis and response to infection by inducing Mcm3 and Mcm5 expression and enabling S-phase entry.Chong T. LuoHatice U. OsmanbeyogluMytrang H. DoMichael R. BivonaAhmed ToureDavina KangYuchen XieChristina S. LeslieMing O. LiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chong T. Luo Hatice U. Osmanbeyoglu Mytrang H. Do Michael R. Bivona Ahmed Toure Davina Kang Yuchen Xie Christina S. Leslie Ming O. Li Ets transcription factor GABP controls T cell homeostasis and immunity
description	T cells need to undergo rapid proliferation in response to antigenic stimulation. Here the authors show that the Ets family transcription factor GABP is required for T-cell homeostasis and response to infection by inducing Mcm3 and Mcm5 expression and enabling S-phase entry.
format	article
author	Chong T. Luo Hatice U. Osmanbeyoglu Mytrang H. Do Michael R. Bivona Ahmed Toure Davina Kang Yuchen Xie Christina S. Leslie Ming O. Li
author_facet	Chong T. Luo Hatice U. Osmanbeyoglu Mytrang H. Do Michael R. Bivona Ahmed Toure Davina Kang Yuchen Xie Christina S. Leslie Ming O. Li
author_sort	Chong T. Luo
title	Ets transcription factor GABP controls T cell homeostasis and immunity
title_short	Ets transcription factor GABP controls T cell homeostasis and immunity
title_full	Ets transcription factor GABP controls T cell homeostasis and immunity
title_fullStr	Ets transcription factor GABP controls T cell homeostasis and immunity
title_full_unstemmed	Ets transcription factor GABP controls T cell homeostasis and immunity
title_sort	ets transcription factor gabp controls t cell homeostasis and immunity
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/50e6f5509f404eff9801e85bc16331be
work_keys_str_mv	AT chongtluo etstranscriptionfactorgabpcontrolstcellhomeostasisandimmunity AT haticeuosmanbeyoglu etstranscriptionfactorgabpcontrolstcellhomeostasisandimmunity AT mytranghdo etstranscriptionfactorgabpcontrolstcellhomeostasisandimmunity AT michaelrbivona etstranscriptionfactorgabpcontrolstcellhomeostasisandimmunity AT ahmedtoure etstranscriptionfactorgabpcontrolstcellhomeostasisandimmunity AT davinakang etstranscriptionfactorgabpcontrolstcellhomeostasisandimmunity AT yuchenxie etstranscriptionfactorgabpcontrolstcellhomeostasisandimmunity AT christinasleslie etstranscriptionfactorgabpcontrolstcellhomeostasisandimmunity AT mingoli etstranscriptionfactorgabpcontrolstcellhomeostasisandimmunity
_version_	1718382206582259712

Ets transcription factor GABP controls T cell homeostasis and immunity

Ejemplares similares