SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms

There has been limited research on the role of the mucosal immune response to SARS-CoV-2 infection. Here, the authors perform a prospective observational household study and find that mucosal antibody responses are associated with decreased viral load and faster resolution of systemic symptoms.

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Autores principales:	Janeri Fröberg, Joshua Gillard, Ria Philipsen, Kjerstin Lanke, Joyce Rust, Diana van Tuijl, Karina Teelen, Teun Bousema, Elles Simonetti, Christa E. van der Gaast-de Jongh, Mariska Bos, Frank J. van Kuppeveld, Berend-Jan Bosch, Marrigje Nabuurs-Franssen, Nannet van der Geest-Blankert, Charlotte van Daal, Martijn A. Huynen, Marien I. de Jonge, Dimitri A. Diavatopoulos
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/50f02a2039984e818d1c4dc6db699767
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spelling	oai:doaj.org-article:50f02a2039984e818d1c4dc6db6997672021-12-02T18:14:31ZSARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms10.1038/s41467-021-25949-x2041-1723https://doaj.org/article/50f02a2039984e818d1c4dc6db6997672021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25949-xhttps://doaj.org/toc/2041-1723There has been limited research on the role of the mucosal immune response to SARS-CoV-2 infection. Here, the authors perform a prospective observational household study and find that mucosal antibody responses are associated with decreased viral load and faster resolution of systemic symptoms.Janeri FröbergJoshua GillardRia PhilipsenKjerstin LankeJoyce RustDiana van TuijlKarina TeelenTeun BousemaElles SimonettiChrista E. van der Gaast-de JonghMariska BosFrank J. van KuppeveldBerend-Jan BoschMarrigje Nabuurs-FranssenNannet van der Geest-BlankertCharlotte van DaalMartijn A. HuynenMarien I. de JongeDimitri A. DiavatopoulosNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Janeri Fröberg Joshua Gillard Ria Philipsen Kjerstin Lanke Joyce Rust Diana van Tuijl Karina Teelen Teun Bousema Elles Simonetti Christa E. van der Gaast-de Jongh Mariska Bos Frank J. van Kuppeveld Berend-Jan Bosch Marrigje Nabuurs-Franssen Nannet van der Geest-Blankert Charlotte van Daal Martijn A. Huynen Marien I. de Jonge Dimitri A. Diavatopoulos SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms
description	There has been limited research on the role of the mucosal immune response to SARS-CoV-2 infection. Here, the authors perform a prospective observational household study and find that mucosal antibody responses are associated with decreased viral load and faster resolution of systemic symptoms.
format	article
author	Janeri Fröberg Joshua Gillard Ria Philipsen Kjerstin Lanke Joyce Rust Diana van Tuijl Karina Teelen Teun Bousema Elles Simonetti Christa E. van der Gaast-de Jongh Mariska Bos Frank J. van Kuppeveld Berend-Jan Bosch Marrigje Nabuurs-Franssen Nannet van der Geest-Blankert Charlotte van Daal Martijn A. Huynen Marien I. de Jonge Dimitri A. Diavatopoulos
author_facet	Janeri Fröberg Joshua Gillard Ria Philipsen Kjerstin Lanke Joyce Rust Diana van Tuijl Karina Teelen Teun Bousema Elles Simonetti Christa E. van der Gaast-de Jongh Mariska Bos Frank J. van Kuppeveld Berend-Jan Bosch Marrigje Nabuurs-Franssen Nannet van der Geest-Blankert Charlotte van Daal Martijn A. Huynen Marien I. de Jonge Dimitri A. Diavatopoulos
author_sort	Janeri Fröberg
title	SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms
title_short	SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms
title_full	SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms
title_fullStr	SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms
title_full_unstemmed	SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms
title_sort	sars-cov-2 mucosal antibody development and persistence and their relation to viral load and covid-19 symptoms
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/50f02a2039984e818d1c4dc6db699767
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SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms

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