Foxp3+ Tregs are recruited to the retina to repair pathological angiogenesis
The local immune responses in the eye are attenuated to preserve sight. Surprisingly, Deliyanti et al. show that regulatory T cells (Tregs) take an active role in protecting the eye from neovascularization in oxygen-induced retinopathy, and that interventions that augment the retinal Treg numbers re...
Saved in:
| Main Authors: | Devy Deliyanti, Dean M. Talia, Tong Zhu, Mhairi J. Maxwell, Alex Agrotis, Jack R. Jerome, Emily M. Hargreaves, Steven Gerondakis, Margaret L. Hibbs, Fabienne Mackay, Jennifer L. Wilkinson-Berka |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2017
|
| Subjects: | |
| Online Access: | https://doaj.org/article/50f3675a81e5466f9c5075205f5d2ecb |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The transcription factor Foxp1 preserves integrity of an active Foxp3 locus in extrathymic Treg cells
by: Sayantani Ghosh, et al.
Published: (2018) -
Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells
by: Stephanie Downs-Canner, et al.
Published: (2017) -
Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function
by: Jianbing Huang, et al.
Published: (2017) -
Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases
by: Yuxiu Xu, et al.
Published: (2021) -
Type 1 diabetes vaccine candidates promote human Foxp3+Treg induction in humanized mice
by: Isabelle Serr, et al.
Published: (2016)