Unlipidated outer membrane protein Omp16 (U-Omp16) from Brucella spp. as nasal adjuvant induces a Th1 immune response and modulates the Th2 allergic response to cow's milk proteins.

Unlipidated outer membrane protein Omp16 (U-Omp16) from Brucella spp. as nasal adjuvant induces a Th1 immune response and modulates the Th2 allergic response to cow's milk proteins.

The discovery of novel mucosal adjuvants will help to develop new formulations to control infectious and allergic diseases. In this work we demonstrate that U-Omp16 from Brucella spp. delivered by the nasal route (i.n.) induced an inflammatory immune response in bronchoalveolar lavage (BAL) and lung...

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Autores principales: Andrés E Ibañez, Paola Smaldini, Lorena M Coria, María V Delpino, Lucila G G Pacífico, Sergio C Oliveira, Gabriela S Risso, Karina A Pasquevich, Carlos Alberto Fossati, Guillermo H Giambartolomei, Guillermo H Docena, Juliana Cassataro
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/510bad422a1e42fcb66b30a9dc3461b8
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