Treatment of myopic choroidal neovascularization with intravitreal ranibizumab injections: the role of age

Dimitrios Karagiannis,1 Georgios A Kontadakis,1,2 Konstantinos Kaprinis,1 Athanassios Giarmoukakis,2 lias Georgalas,3 Efstratios A Parikakis,1 Miltiadis K Tsilimbaris2 1Ophthalmiatreio Eye Hospital of Athens, Athens, Greece; 2Department of Ophthalmology, University Hospital of Heraklion, University...

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Autores principales:	Karagiannis D, Kontadakis GA, Kaprinis K, Giarmoukakis A, Georgalas I, Parikakis EA, Tsilimbaris MK
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	myopic choroidal neovascularization intravitreal injection ranibizumab pathologic myopia Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/510d9a96b309404d96f1020230752a71
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spelling	oai:doaj.org-article:510d9a96b309404d96f1020230752a712021-12-02T06:17:14ZTreatment of myopic choroidal neovascularization with intravitreal ranibizumab injections: the role of age1177-5483https://doaj.org/article/510d9a96b309404d96f1020230752a712017-06-01T00:00:00Zhttps://www.dovepress.com/treatment-of-myopic-choroidal-neovascularization-with-intravitreal-ran-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Dimitrios Karagiannis,1 Georgios A Kontadakis,1,2 Konstantinos Kaprinis,1 Athanassios Giarmoukakis,2 lias Georgalas,3 Efstratios A Parikakis,1 Miltiadis K Tsilimbaris2 1Ophthalmiatreio Eye Hospital of Athens, Athens, Greece; 2Department of Ophthalmology, University Hospital of Heraklion, University of Crete, Heraklio, Greece; 3Department of Ophthalmology, University of Athens, Athens, Greece Purpose: The aim of this study was to explore the role of age as a prognostic factor for the outcome of myopic choroidal neovascularization (CNV) treatment with intravitreal ranibizumab injections.Methods: A retrospective review of charts of patients treated with intravitreal injections of ranibizumab for the treatment of myopic CNV was done. Patients with other ophthalmic disease were excluded. Patients were followed for at least 2 years. The correlation between age and the change in visual acuity and the number of injections during treatment was investigated.Results: Age of the patients was significantly correlated with the number of injections that the patients received (Pearson’s r=0.585, P=0.005). Also, it was significantly correlated with improvement in corrected distance visual acuity, defined as the difference between final and initial LogMAR corrected distance visual acuity (Pearson’s r=0.614, P=0.003).Conclusion: Age significantly affects the visual outcome of myopic CNV treatment with ranibizumab. Younger patients in our study needed fewer intravitreal injections and achieved a more significant improvement in vision. Keywords: myopic choroidal neovascularization, intravitreal injection, ranibizumab, pathologic myopiaKaragiannis DKontadakis GAKaprinis KGiarmoukakis AGeorgalas IParikakis EATsilimbaris MKDove Medical Pressarticlemyopic choroidal neovascularizationintravitreal injectionranibizumabpathologic myopiaOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 11, Pp 1197-1201 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	myopic choroidal neovascularization intravitreal injection ranibizumab pathologic myopia Ophthalmology RE1-994
spellingShingle	myopic choroidal neovascularization intravitreal injection ranibizumab pathologic myopia Ophthalmology RE1-994 Karagiannis D Kontadakis GA Kaprinis K Giarmoukakis A Georgalas I Parikakis EA Tsilimbaris MK Treatment of myopic choroidal neovascularization with intravitreal ranibizumab injections: the role of age
description	Dimitrios Karagiannis,1 Georgios A Kontadakis,1,2 Konstantinos Kaprinis,1 Athanassios Giarmoukakis,2 lias Georgalas,3 Efstratios A Parikakis,1 Miltiadis K Tsilimbaris2 1Ophthalmiatreio Eye Hospital of Athens, Athens, Greece; 2Department of Ophthalmology, University Hospital of Heraklion, University of Crete, Heraklio, Greece; 3Department of Ophthalmology, University of Athens, Athens, Greece Purpose: The aim of this study was to explore the role of age as a prognostic factor for the outcome of myopic choroidal neovascularization (CNV) treatment with intravitreal ranibizumab injections.Methods: A retrospective review of charts of patients treated with intravitreal injections of ranibizumab for the treatment of myopic CNV was done. Patients with other ophthalmic disease were excluded. Patients were followed for at least 2 years. The correlation between age and the change in visual acuity and the number of injections during treatment was investigated.Results: Age of the patients was significantly correlated with the number of injections that the patients received (Pearson’s r=0.585, P=0.005). Also, it was significantly correlated with improvement in corrected distance visual acuity, defined as the difference between final and initial LogMAR corrected distance visual acuity (Pearson’s r=0.614, P=0.003).Conclusion: Age significantly affects the visual outcome of myopic CNV treatment with ranibizumab. Younger patients in our study needed fewer intravitreal injections and achieved a more significant improvement in vision. Keywords: myopic choroidal neovascularization, intravitreal injection, ranibizumab, pathologic myopia
format	article
author	Karagiannis D Kontadakis GA Kaprinis K Giarmoukakis A Georgalas I Parikakis EA Tsilimbaris MK
author_facet	Karagiannis D Kontadakis GA Kaprinis K Giarmoukakis A Georgalas I Parikakis EA Tsilimbaris MK
author_sort	Karagiannis D
title	Treatment of myopic choroidal neovascularization with intravitreal ranibizumab injections: the role of age
title_short	Treatment of myopic choroidal neovascularization with intravitreal ranibizumab injections: the role of age
title_full	Treatment of myopic choroidal neovascularization with intravitreal ranibizumab injections: the role of age
title_fullStr	Treatment of myopic choroidal neovascularization with intravitreal ranibizumab injections: the role of age
title_full_unstemmed	Treatment of myopic choroidal neovascularization with intravitreal ranibizumab injections: the role of age
title_sort	treatment of myopic choroidal neovascularization with intravitreal ranibizumab injections: the role of age
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/510d9a96b309404d96f1020230752a71
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Treatment of myopic choroidal neovascularization with intravitreal ranibizumab injections: the role of age

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