Taiwan Society of Colon and Rectal Surgeons Consensus on mCRC Treatment

Therapeutic options for metastatic CRC (mCRC) have changed significantly in recent years, greatly increasing the complexity of therapeutic decision-making. Although oncology guidelines have helped improve the care process, guidelines may also limit the flexibility to individualize in-clinic decision...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hong-Hwa Chen, Tao-Wei Ke, Ching-Wen Huang, Jeng-Kae Jiang, Chou-Chen Chen, Yao-Yu Hsieh, Hao-Wei Teng, Bo-Wen Lin, Yi-Hsin Liang, Yu-Li Su, Hung-Chih Hsu, Feng-Che Kuan, Yenn-Hwei Chou, Johnson Lin, Ben-Ren Lin, Yu-Yao Chang, Jaw-Yuan Wang
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	Taiwan metastatic colorectal cancer treatment consensus molecular biomarker disease management in real world practice Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/51101c1ebda440049aea4e70c061c41a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:51101c1ebda440049aea4e70c061c41a
record_format	dspace
spelling	oai:doaj.org-article:51101c1ebda440049aea4e70c061c41a2021-11-15T12:57:08ZTaiwan Society of Colon and Rectal Surgeons Consensus on mCRC Treatment2234-943X10.3389/fonc.2021.764912https://doaj.org/article/51101c1ebda440049aea4e70c061c41a2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fonc.2021.764912/fullhttps://doaj.org/toc/2234-943XTherapeutic options for metastatic CRC (mCRC) have changed significantly in recent years, greatly increasing the complexity of therapeutic decision-making. Although oncology guidelines have helped improve the care process, guidelines may also limit the flexibility to individualize in-clinic decision-making. This consensus paper addresses specific gaps in the current international guidelines to assist Taiwanese colon and rectal experts make specific therapeutic choices. Over 3 years and three meetings with selected experts on “real-world” Taiwanese practice patterns for mCRC, consensus was achieved. The experts also discussed specific questions during in-depth one-on-one consultation. Outcomes of the discussion were then correlated with published evidence by an independent medical writer. The final consensus includes clinically implementable recommendations to provide guidance in treating Taiwanese mCRC patients. The consensus includes criteria for defining fit and unfit intensive treatment patients, treatment goals, treatment considerations of molecular profiles, treatment consideration, and optimal treatment choices between different patient archetypes, including optimal treatment options based on RAS, BRAF, and microsatellite instability (MSI) status. This consensus paper is the second in the Taiwan Society of Colon and Rectal Surgeons (TSCRS) Consensus series to address unmet gaps in guideline recommendations in lieu of Taiwanese mCRC management. Meticulous discussions with experts, the multidisciplinary nature of the working group, and the final drafting of the consensus by independent medical professionals have contributed to the strong scientific value of this consensus.Hong-Hwa ChenTao-Wei KeChing-Wen HuangChing-Wen HuangJeng-Kae JiangChou-Chen ChenYao-Yu HsiehHao-Wei TengBo-Wen LinYi-Hsin LiangYu-Li SuHung-Chih HsuFeng-Che KuanYenn-Hwei ChouJohnson LinBen-Ren LinYu-Yao ChangJaw-Yuan WangJaw-Yuan WangJaw-Yuan WangJaw-Yuan WangFrontiers Media S.A.articleTaiwanmetastatic colorectal cancertreatment consensusmolecular biomarkerdisease management in real world practiceNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENFrontiers in Oncology, Vol 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Taiwan metastatic colorectal cancer treatment consensus molecular biomarker disease management in real world practice Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	Taiwan metastatic colorectal cancer treatment consensus molecular biomarker disease management in real world practice Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Hong-Hwa Chen Tao-Wei Ke Ching-Wen Huang Ching-Wen Huang Jeng-Kae Jiang Chou-Chen Chen Yao-Yu Hsieh Hao-Wei Teng Bo-Wen Lin Yi-Hsin Liang Yu-Li Su Hung-Chih Hsu Feng-Che Kuan Yenn-Hwei Chou Johnson Lin Ben-Ren Lin Yu-Yao Chang Jaw-Yuan Wang Jaw-Yuan Wang Jaw-Yuan Wang Jaw-Yuan Wang Taiwan Society of Colon and Rectal Surgeons Consensus on mCRC Treatment
description	Therapeutic options for metastatic CRC (mCRC) have changed significantly in recent years, greatly increasing the complexity of therapeutic decision-making. Although oncology guidelines have helped improve the care process, guidelines may also limit the flexibility to individualize in-clinic decision-making. This consensus paper addresses specific gaps in the current international guidelines to assist Taiwanese colon and rectal experts make specific therapeutic choices. Over 3 years and three meetings with selected experts on “real-world” Taiwanese practice patterns for mCRC, consensus was achieved. The experts also discussed specific questions during in-depth one-on-one consultation. Outcomes of the discussion were then correlated with published evidence by an independent medical writer. The final consensus includes clinically implementable recommendations to provide guidance in treating Taiwanese mCRC patients. The consensus includes criteria for defining fit and unfit intensive treatment patients, treatment goals, treatment considerations of molecular profiles, treatment consideration, and optimal treatment choices between different patient archetypes, including optimal treatment options based on RAS, BRAF, and microsatellite instability (MSI) status. This consensus paper is the second in the Taiwan Society of Colon and Rectal Surgeons (TSCRS) Consensus series to address unmet gaps in guideline recommendations in lieu of Taiwanese mCRC management. Meticulous discussions with experts, the multidisciplinary nature of the working group, and the final drafting of the consensus by independent medical professionals have contributed to the strong scientific value of this consensus.
format	article
author	Hong-Hwa Chen Tao-Wei Ke Ching-Wen Huang Ching-Wen Huang Jeng-Kae Jiang Chou-Chen Chen Yao-Yu Hsieh Hao-Wei Teng Bo-Wen Lin Yi-Hsin Liang Yu-Li Su Hung-Chih Hsu Feng-Che Kuan Yenn-Hwei Chou Johnson Lin Ben-Ren Lin Yu-Yao Chang Jaw-Yuan Wang Jaw-Yuan Wang Jaw-Yuan Wang Jaw-Yuan Wang
author_facet	Hong-Hwa Chen Tao-Wei Ke Ching-Wen Huang Ching-Wen Huang Jeng-Kae Jiang Chou-Chen Chen Yao-Yu Hsieh Hao-Wei Teng Bo-Wen Lin Yi-Hsin Liang Yu-Li Su Hung-Chih Hsu Feng-Che Kuan Yenn-Hwei Chou Johnson Lin Ben-Ren Lin Yu-Yao Chang Jaw-Yuan Wang Jaw-Yuan Wang Jaw-Yuan Wang Jaw-Yuan Wang
author_sort	Hong-Hwa Chen
title	Taiwan Society of Colon and Rectal Surgeons Consensus on mCRC Treatment
title_short	Taiwan Society of Colon and Rectal Surgeons Consensus on mCRC Treatment
title_full	Taiwan Society of Colon and Rectal Surgeons Consensus on mCRC Treatment
title_fullStr	Taiwan Society of Colon and Rectal Surgeons Consensus on mCRC Treatment
title_full_unstemmed	Taiwan Society of Colon and Rectal Surgeons Consensus on mCRC Treatment
title_sort	taiwan society of colon and rectal surgeons consensus on mcrc treatment
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/51101c1ebda440049aea4e70c061c41a
work_keys_str_mv	AT honghwachen taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT taoweike taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT chingwenhuang taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT chingwenhuang taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT jengkaejiang taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT chouchenchen taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT yaoyuhsieh taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT haoweiteng taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT bowenlin taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT yihsinliang taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT yulisu taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT hungchihhsu taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT fengchekuan taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT yennhweichou taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT johnsonlin taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT benrenlin taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT yuyaochang taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT jawyuanwang taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT jawyuanwang taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT jawyuanwang taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment AT jawyuanwang taiwansocietyofcolonandrectalsurgeonsconsensusonmcrctreatment
_version_	1718428433194680320

Taiwan Society of Colon and Rectal Surgeons Consensus on mCRC Treatment

Ejemplares similares