Preparation and characterization of an iron oxide-hydroxyapatite nanocomposite for potential bone cancer therapy

Murugesan Sneha, Nachiappan Meenakshi Sundaram Department of Biomedical Engineering, PSG College of Technology, Tamil Nadu, India Abstract: Recently, multifunctional magnetic nanostructures have been found to have potential applications in biomedical and tissue engineering. Iron oxide nanoparticle...

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Main Authors:	Sneha M, Sundaram NM
Format:	article
Language:	EN
Published:	Dove Medical Press 2015
Subjects:	Medicine (General) R5-920
Online Access:	https://doaj.org/article/511b51d649f64865bb73af46ad61cf94
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spelling	oai:doaj.org-article:511b51d649f64865bb73af46ad61cf942021-12-02T01:32:33ZPreparation and characterization of an iron oxide-hydroxyapatite nanocomposite for potential bone cancer therapy1178-2013https://doaj.org/article/511b51d649f64865bb73af46ad61cf942015-10-01T00:00:00Zhttps://www.dovepress.com/preparation-and-characterization-of-an-iron-oxide-hydroxyapatite-nanoc-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Murugesan Sneha, Nachiappan Meenakshi Sundaram Department of Biomedical Engineering, PSG College of Technology, Tamil Nadu, India Abstract: Recently, multifunctional magnetic nanostructures have been found to have potential applications in biomedical and tissue engineering. Iron oxide nanoparticles are biocompatible and have distinctive magnetic properties that allow their use in vivo for drug delivery and hyperthermia, and as T2 contrast agents for magnetic resonance imaging. Hydroxyapatite is used frequently due to its well-known biocompatibility, bioactivity, and lack of toxicity, so a combination of iron oxide and hydroxyapatite materials could be useful because hydroxyapatite has better bone-bonding ability. In this study, we prepared nanocomposites of iron oxide and hydroxyapatite and analyzed their physicochemical properties. The results suggest that these composites have superparamagnetic as well as biocompatible properties. This type of material architecture would be well suited for bone cancer therapy and other biomedical applications. Keywords: iron oxide, hydroxyapatite, nanocomposite, superparamagnetic, bone cancerSneha MSundaram NMDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2015, Iss Supplement 1 Challenges in biomaterials research, Pp 99-106 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Sneha M Sundaram NM Preparation and characterization of an iron oxide-hydroxyapatite nanocomposite for potential bone cancer therapy
description	Murugesan Sneha, Nachiappan Meenakshi Sundaram Department of Biomedical Engineering, PSG College of Technology, Tamil Nadu, India Abstract: Recently, multifunctional magnetic nanostructures have been found to have potential applications in biomedical and tissue engineering. Iron oxide nanoparticles are biocompatible and have distinctive magnetic properties that allow their use in vivo for drug delivery and hyperthermia, and as T2 contrast agents for magnetic resonance imaging. Hydroxyapatite is used frequently due to its well-known biocompatibility, bioactivity, and lack of toxicity, so a combination of iron oxide and hydroxyapatite materials could be useful because hydroxyapatite has better bone-bonding ability. In this study, we prepared nanocomposites of iron oxide and hydroxyapatite and analyzed their physicochemical properties. The results suggest that these composites have superparamagnetic as well as biocompatible properties. This type of material architecture would be well suited for bone cancer therapy and other biomedical applications. Keywords: iron oxide, hydroxyapatite, nanocomposite, superparamagnetic, bone cancer
format	article
author	Sneha M Sundaram NM
author_facet	Sneha M Sundaram NM
author_sort	Sneha M
title	Preparation and characterization of an iron oxide-hydroxyapatite nanocomposite for potential bone cancer therapy
title_short	Preparation and characterization of an iron oxide-hydroxyapatite nanocomposite for potential bone cancer therapy
title_full	Preparation and characterization of an iron oxide-hydroxyapatite nanocomposite for potential bone cancer therapy
title_fullStr	Preparation and characterization of an iron oxide-hydroxyapatite nanocomposite for potential bone cancer therapy
title_full_unstemmed	Preparation and characterization of an iron oxide-hydroxyapatite nanocomposite for potential bone cancer therapy
title_sort	preparation and characterization of an iron oxide-hydroxyapatite nanocomposite for potential bone cancer therapy
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/511b51d649f64865bb73af46ad61cf94
work_keys_str_mv	AT sneham preparationandcharacterizationofanironoxidehydroxyapatitenanocompositeforpotentialbonecancertherapy AT sundaramnm preparationandcharacterizationofanironoxidehydroxyapatitenanocompositeforpotentialbonecancertherapy
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Preparation and characterization of an iron oxide-hydroxyapatite nanocomposite for potential bone cancer therapy

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