Positron emission tomography imaging with 89Zr-labeled anti-CD8 cys-diabody reveals CD8+ cell infiltration during oncolytic virus therapy in a glioma murine model

Positron emission tomography imaging with 89Zr-labeled anti-CD8 cys-diabody reveals CD8+ cell infiltration during oncolytic virus therapy in a glioma murine model

Abstract Determination of treatment response to immunotherapy in glioblastoma multiforme (GBM) is a process which can take months. Detection of CD8+ T cell recruitment to the tumor with a noninvasive imaging modality such as positron emission tomography (PET) may allow for tumor characterization and...

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Autores principales: Benjamin B. Kasten, Hailey A. Houson, Jennifer M. Coleman, Jianmei W. Leavenworth, James M. Markert, Anna M. Wu, Felix Salazar, Richard Tavaré, Adriana V. F. Massicano, G. Yancey Gillespie, Suzanne E. Lapi, Jason M. Warram, Anna G. Sorace
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/5121b4300f984e959794f9b641be16e2
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