A compendium of chromatin contact maps reflecting regulation by chromatin remodelers in budding yeast

The effect of ATP-dependent chromatin remodelers on 3D genome organization has not been well studied. Here the authors employ in situ Hi-C with an auxin-inducible degron system to degrade chromatin remodelers in yeast to find that the 3D structure of chromatin collapses in their absence. The chromat...

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Autores principales: Hyelim Jo, Taemook Kim, Yujin Chun, Inkyung Jung, Daeyoup Lee
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5121d4a4297444e6829d50da1bb0236a
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spelling oai:doaj.org-article:5121d4a4297444e6829d50da1bb0236a2021-11-08T11:08:31ZA compendium of chromatin contact maps reflecting regulation by chromatin remodelers in budding yeast10.1038/s41467-021-26629-62041-1723https://doaj.org/article/5121d4a4297444e6829d50da1bb0236a2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26629-6https://doaj.org/toc/2041-1723The effect of ATP-dependent chromatin remodelers on 3D genome organization has not been well studied. Here the authors employ in situ Hi-C with an auxin-inducible degron system to degrade chromatin remodelers in yeast to find that the 3D structure of chromatin collapses in their absence. The chromatin remodeling can modulate 3D architecture depending on chromosomal context and cell cycle stage.Hyelim JoTaemook KimYujin ChunInkyung JungDaeyoup LeeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hyelim Jo
Taemook Kim
Yujin Chun
Inkyung Jung
Daeyoup Lee
A compendium of chromatin contact maps reflecting regulation by chromatin remodelers in budding yeast
description The effect of ATP-dependent chromatin remodelers on 3D genome organization has not been well studied. Here the authors employ in situ Hi-C with an auxin-inducible degron system to degrade chromatin remodelers in yeast to find that the 3D structure of chromatin collapses in their absence. The chromatin remodeling can modulate 3D architecture depending on chromosomal context and cell cycle stage.
format article
author Hyelim Jo
Taemook Kim
Yujin Chun
Inkyung Jung
Daeyoup Lee
author_facet Hyelim Jo
Taemook Kim
Yujin Chun
Inkyung Jung
Daeyoup Lee
author_sort Hyelim Jo
title A compendium of chromatin contact maps reflecting regulation by chromatin remodelers in budding yeast
title_short A compendium of chromatin contact maps reflecting regulation by chromatin remodelers in budding yeast
title_full A compendium of chromatin contact maps reflecting regulation by chromatin remodelers in budding yeast
title_fullStr A compendium of chromatin contact maps reflecting regulation by chromatin remodelers in budding yeast
title_full_unstemmed A compendium of chromatin contact maps reflecting regulation by chromatin remodelers in budding yeast
title_sort compendium of chromatin contact maps reflecting regulation by chromatin remodelers in budding yeast
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/5121d4a4297444e6829d50da1bb0236a
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