Embracing the dropouts in single-cell RNA-seq analysis

The analysis of RNA-seq data is complicated by dropouts, and these are usually treated as a problem to be addressed. Here, Peng Qiu uses dropouts as a source of information and presents a co-occurrence clustering algorithm to cluster cells based on the dropout pattern; this could be a complementary...

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Autor principal: Peng Qiu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/512620a580e14a5599691b08db28363c
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spelling oai:doaj.org-article:512620a580e14a5599691b08db28363c2021-12-02T15:39:07ZEmbracing the dropouts in single-cell RNA-seq analysis10.1038/s41467-020-14976-92041-1723https://doaj.org/article/512620a580e14a5599691b08db28363c2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14976-9https://doaj.org/toc/2041-1723The analysis of RNA-seq data is complicated by dropouts, and these are usually treated as a problem to be addressed. Here, Peng Qiu uses dropouts as a source of information and presents a co-occurrence clustering algorithm to cluster cells based on the dropout pattern; this could be a complementary approach to existing methods.Peng QiuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Peng Qiu
Embracing the dropouts in single-cell RNA-seq analysis
description The analysis of RNA-seq data is complicated by dropouts, and these are usually treated as a problem to be addressed. Here, Peng Qiu uses dropouts as a source of information and presents a co-occurrence clustering algorithm to cluster cells based on the dropout pattern; this could be a complementary approach to existing methods.
format article
author Peng Qiu
author_facet Peng Qiu
author_sort Peng Qiu
title Embracing the dropouts in single-cell RNA-seq analysis
title_short Embracing the dropouts in single-cell RNA-seq analysis
title_full Embracing the dropouts in single-cell RNA-seq analysis
title_fullStr Embracing the dropouts in single-cell RNA-seq analysis
title_full_unstemmed Embracing the dropouts in single-cell RNA-seq analysis
title_sort embracing the dropouts in single-cell rna-seq analysis
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/512620a580e14a5599691b08db28363c
work_keys_str_mv AT pengqiu embracingthedropoutsinsinglecellrnaseqanalysis
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