Determinants of Opportunistic Infections Among HIV-Positive Patients on HAART in Debre Berhan Referral Hospital, North Shoa Zone, Ethiopia, 2020: A Case–Control Study

Determinants of Opportunistic Infections Among HIV-Positive Patients on HAART in Debre Berhan Referral Hospital, North Shoa Zone, Ethiopia, 2020: A Case–Control Study

Abrham Shitaw Tewachew,1 Wassie Negash Mekonnen,2 Abinet Dagnaw Mekuria,2 Yosef Eshetie Amare3 1Department of Medicine, Institute of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, Ethiopia; 2Department of Public Health, Institute of Medicine and Health Sciences, Debre Berhan Un...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Tewachew AS, Mekonnen WN, Mekuria AD, Amare YE
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2021
Materias:
opportunistic infections
hiv/aids
haart
cd4
debre berhan
ethiopia
Immunologic diseases. Allergy
RC581-607
Acceso en línea:https://doaj.org/article/512aa5d262ec4889b8d4db4f9e89990b
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:512aa5d262ec4889b8d4db4f9e89990b
record_format dspace
spelling oai:doaj.org-article:512aa5d262ec4889b8d4db4f9e89990b2021-12-02T15:59:21ZDeterminants of Opportunistic Infections Among HIV-Positive Patients on HAART in Debre Berhan Referral Hospital, North Shoa Zone, Ethiopia, 2020: A Case–Control Study1179-1373https://doaj.org/article/512aa5d262ec4889b8d4db4f9e89990b2021-03-01T00:00:00Zhttps://www.dovepress.com/determinants-of-opportunistic-infections-among-hiv-positive-patients-o-peer-reviewed-article-HIVhttps://doaj.org/toc/1179-1373Abrham Shitaw Tewachew,1 Wassie Negash Mekonnen,2 Abinet Dagnaw Mekuria,2 Yosef Eshetie Amare3 1Department of Medicine, Institute of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, Ethiopia; 2Department of Public Health, Institute of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, Ethiopia; 3Department of Biomedical Sciences, Institute of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, EthiopiaCorrespondence: Yosef Eshetie AmareDepartment of Biomedical Sciences, Institute of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, EthiopiaTel +251910966364Email yophy2006@gmail.comIntroduction: Opportunistic infections are an illness that exists more frequently and is more severe in people with HIV. In HIV/AIDS patients, opportunistic infections still cause morbidity and mortality even after the era of highly active antiretroviral therapy (HAART) and most patients die as direct or indirect complications of opportunistic infections. This study was aimed to identify the determinants for the occurrence of opportunistic infections in HIV-positive patients having HAART follow-up in DBRH, Debre Berhan, Ethiopia.Methods: A total of 339 study subjects were involved under institution-based unmatched case–control study design and simple random sampling technique. A pre-tested structured questionnaire was used for data collection. Data were entered using Epidata version 3.1 and analyzed for descriptive and logistic regression models by SPSS version 21. A P-value of less than 0.05 was considered as statistically significant.Results: After adjusting potential confounders, drinking alcohol (AOR=3.12, 95% CI: 1.07– 9.06), BMI < 18.5 (AOR= 3.36, 95% CI: 1.49– 7.55), previous history of opportunistic infections (AOR= 2.96, 95% CI: 1.51– 5.8) were independent predictors of opportunistic infections in people living with HIV/AIDS on HAART.Conclusion: In this study, the poor clinical and biochemical status, and behavioral factors were being the predictors of the occurrence of opportunistic infections. HIV/AIDS patients must be assessed and screened for opportunistic infections.Keywords: opportunistic infections, HIV/AIDS, HAART, CD4, Debre Berhan, EthiopiaTewachew ASMekonnen WNMekuria ADAmare YEDove Medical Pressarticleopportunistic infectionshiv/aidshaartcd4debre berhanethiopiaImmunologic diseases. AllergyRC581-607ENHIV/AIDS: Research and Palliative Care, Vol Volume 13, Pp 337-347 (2021)
institution DOAJ
collection DOAJ
language EN
topic opportunistic infections
hiv/aids
haart
cd4
debre berhan
ethiopia
Immunologic diseases. Allergy
RC581-607
spellingShingle opportunistic infections
hiv/aids
haart
cd4
debre berhan
ethiopia
Immunologic diseases. Allergy
RC581-607
Tewachew AS
Mekonnen WN
Mekuria AD
Amare YE
Determinants of Opportunistic Infections Among HIV-Positive Patients on HAART in Debre Berhan Referral Hospital, North Shoa Zone, Ethiopia, 2020: A Case–Control Study
description Abrham Shitaw Tewachew,1 Wassie Negash Mekonnen,2 Abinet Dagnaw Mekuria,2 Yosef Eshetie Amare3 1Department of Medicine, Institute of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, Ethiopia; 2Department of Public Health, Institute of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, Ethiopia; 3Department of Biomedical Sciences, Institute of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, EthiopiaCorrespondence: Yosef Eshetie AmareDepartment of Biomedical Sciences, Institute of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, EthiopiaTel +251910966364Email yophy2006@gmail.comIntroduction: Opportunistic infections are an illness that exists more frequently and is more severe in people with HIV. In HIV/AIDS patients, opportunistic infections still cause morbidity and mortality even after the era of highly active antiretroviral therapy (HAART) and most patients die as direct or indirect complications of opportunistic infections. This study was aimed to identify the determinants for the occurrence of opportunistic infections in HIV-positive patients having HAART follow-up in DBRH, Debre Berhan, Ethiopia.Methods: A total of 339 study subjects were involved under institution-based unmatched case–control study design and simple random sampling technique. A pre-tested structured questionnaire was used for data collection. Data were entered using Epidata version 3.1 and analyzed for descriptive and logistic regression models by SPSS version 21. A P-value of less than 0.05 was considered as statistically significant.Results: After adjusting potential confounders, drinking alcohol (AOR=3.12, 95% CI: 1.07– 9.06), BMI < 18.5 (AOR= 3.36, 95% CI: 1.49– 7.55), previous history of opportunistic infections (AOR= 2.96, 95% CI: 1.51– 5.8) were independent predictors of opportunistic infections in people living with HIV/AIDS on HAART.Conclusion: In this study, the poor clinical and biochemical status, and behavioral factors were being the predictors of the occurrence of opportunistic infections. HIV/AIDS patients must be assessed and screened for opportunistic infections.Keywords: opportunistic infections, HIV/AIDS, HAART, CD4, Debre Berhan, Ethiopia
format article
author Tewachew AS
Mekonnen WN
Mekuria AD
Amare YE
author_facet Tewachew AS
Mekonnen WN
Mekuria AD
Amare YE
author_sort Tewachew AS
title Determinants of Opportunistic Infections Among HIV-Positive Patients on HAART in Debre Berhan Referral Hospital, North Shoa Zone, Ethiopia, 2020: A Case–Control Study
title_short Determinants of Opportunistic Infections Among HIV-Positive Patients on HAART in Debre Berhan Referral Hospital, North Shoa Zone, Ethiopia, 2020: A Case–Control Study
title_full Determinants of Opportunistic Infections Among HIV-Positive Patients on HAART in Debre Berhan Referral Hospital, North Shoa Zone, Ethiopia, 2020: A Case–Control Study
title_fullStr Determinants of Opportunistic Infections Among HIV-Positive Patients on HAART in Debre Berhan Referral Hospital, North Shoa Zone, Ethiopia, 2020: A Case–Control Study
title_full_unstemmed Determinants of Opportunistic Infections Among HIV-Positive Patients on HAART in Debre Berhan Referral Hospital, North Shoa Zone, Ethiopia, 2020: A Case–Control Study
title_sort determinants of opportunistic infections among hiv-positive patients on haart in debre berhan referral hospital, north shoa zone, ethiopia, 2020: a case–control study
publisher Dove Medical Press
publishDate 2021
url https://doaj.org/article/512aa5d262ec4889b8d4db4f9e89990b
work_keys_str_mv AT tewachewas determinantsofopportunisticinfectionsamonghivpositivepatientsonhaartindebreberhanreferralhospitalnorthshoazoneethiopia2020acasendashcontrolstudy
AT mekonnenwn determinantsofopportunisticinfectionsamonghivpositivepatientsonhaartindebreberhanreferralhospitalnorthshoazoneethiopia2020acasendashcontrolstudy
AT mekuriaad determinantsofopportunisticinfectionsamonghivpositivepatientsonhaartindebreberhanreferralhospitalnorthshoazoneethiopia2020acasendashcontrolstudy
AT amareye determinantsofopportunisticinfectionsamonghivpositivepatientsonhaartindebreberhanreferralhospitalnorthshoazoneethiopia2020acasendashcontrolstudy
_version_ 1718385328799088640

Ejemplares similares