Life-cycle and genome of OtV5, a large DNA virus of the pelagic marine unicellular green alga Ostreococcus tauri.

Large DNA viruses are ubiquitous, infecting diverse organisms ranging from algae to man, and have probably evolved from an ancient common ancestor. In aquatic environments, such algal viruses control blooms and shape the evolution of biodiversity in phytoplankton, but little is known about their bio...

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Autores principales:	Evelyne Derelle, Conchita Ferraz, Marie-Line Escande, Sophie Eychenié, Richard Cooke, Gwenaël Piganeau, Yves Desdevises, Laure Bellec, Hervé Moreau, Nigel Grimsley
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2008
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/512b7a7446b54313b92e930b985d5d1e
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spelling	oai:doaj.org-article:512b7a7446b54313b92e930b985d5d1e2021-11-25T06:12:16ZLife-cycle and genome of OtV5, a large DNA virus of the pelagic marine unicellular green alga Ostreococcus tauri.1932-620310.1371/journal.pone.0002250https://doaj.org/article/512b7a7446b54313b92e930b985d5d1e2008-05-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18509524/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Large DNA viruses are ubiquitous, infecting diverse organisms ranging from algae to man, and have probably evolved from an ancient common ancestor. In aquatic environments, such algal viruses control blooms and shape the evolution of biodiversity in phytoplankton, but little is known about their biological functions. We show that Ostreococcus tauri, the smallest known marine photosynthetic eukaryote, whose genome is completely characterized, is a host for large DNA viruses, and present an analysis of the life-cycle and 186,234 bp long linear genome of OtV5. OtV5 is a lytic phycodnavirus which unexpectedly does not degrade its host chromosomes before the host cell bursts. Analysis of its complete genome sequence confirmed that it lacks expected site-specific endonucleases, and revealed the presence of 16 genes whose predicted functions are novel to this group of viruses. OtV5 carries at least one predicted gene whose protein closely resembles its host counterpart and several other host-like sequences, suggesting that horizontal gene transfers between host and viral genomes may occur frequently on an evolutionary scale. Fifty seven percent of the 268 predicted proteins present no similarities with any known protein in Genbank, underlining the wealth of undiscovered biological diversity present in oceanic viruses, which are estimated to harbour 200Mt of carbon.Evelyne DerelleConchita FerrazMarie-Line EscandeSophie EycheniéRichard CookeGwenaël PiganeauYves DesdevisesLaure BellecHervé MoreauNigel GrimsleyPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 3, Iss 5, p e2250 (2008)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Evelyne Derelle Conchita Ferraz Marie-Line Escande Sophie Eychenié Richard Cooke Gwenaël Piganeau Yves Desdevises Laure Bellec Hervé Moreau Nigel Grimsley Life-cycle and genome of OtV5, a large DNA virus of the pelagic marine unicellular green alga Ostreococcus tauri.
description	Large DNA viruses are ubiquitous, infecting diverse organisms ranging from algae to man, and have probably evolved from an ancient common ancestor. In aquatic environments, such algal viruses control blooms and shape the evolution of biodiversity in phytoplankton, but little is known about their biological functions. We show that Ostreococcus tauri, the smallest known marine photosynthetic eukaryote, whose genome is completely characterized, is a host for large DNA viruses, and present an analysis of the life-cycle and 186,234 bp long linear genome of OtV5. OtV5 is a lytic phycodnavirus which unexpectedly does not degrade its host chromosomes before the host cell bursts. Analysis of its complete genome sequence confirmed that it lacks expected site-specific endonucleases, and revealed the presence of 16 genes whose predicted functions are novel to this group of viruses. OtV5 carries at least one predicted gene whose protein closely resembles its host counterpart and several other host-like sequences, suggesting that horizontal gene transfers between host and viral genomes may occur frequently on an evolutionary scale. Fifty seven percent of the 268 predicted proteins present no similarities with any known protein in Genbank, underlining the wealth of undiscovered biological diversity present in oceanic viruses, which are estimated to harbour 200Mt of carbon.
format	article
author	Evelyne Derelle Conchita Ferraz Marie-Line Escande Sophie Eychenié Richard Cooke Gwenaël Piganeau Yves Desdevises Laure Bellec Hervé Moreau Nigel Grimsley
author_facet	Evelyne Derelle Conchita Ferraz Marie-Line Escande Sophie Eychenié Richard Cooke Gwenaël Piganeau Yves Desdevises Laure Bellec Hervé Moreau Nigel Grimsley
author_sort	Evelyne Derelle
title	Life-cycle and genome of OtV5, a large DNA virus of the pelagic marine unicellular green alga Ostreococcus tauri.
title_short	Life-cycle and genome of OtV5, a large DNA virus of the pelagic marine unicellular green alga Ostreococcus tauri.
title_full	Life-cycle and genome of OtV5, a large DNA virus of the pelagic marine unicellular green alga Ostreococcus tauri.
title_fullStr	Life-cycle and genome of OtV5, a large DNA virus of the pelagic marine unicellular green alga Ostreococcus tauri.
title_full_unstemmed	Life-cycle and genome of OtV5, a large DNA virus of the pelagic marine unicellular green alga Ostreococcus tauri.
title_sort	life-cycle and genome of otv5, a large dna virus of the pelagic marine unicellular green alga ostreococcus tauri.
publisher	Public Library of Science (PLoS)
publishDate	2008
url	https://doaj.org/article/512b7a7446b54313b92e930b985d5d1e
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Life-cycle and genome of OtV5, a large DNA virus of the pelagic marine unicellular green alga Ostreococcus tauri.

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