Self-regenerating giant hyaluronan polymer brushes

Polymer brushes are often used to functionalise surfaces. Here, the authors report on the creation of high-density, regenerating hyaluronan brushes using hyaluronan synthase enzymes which can be patterned by photo-deactivation and demonstrate biocompatibility and resistance to biofilm formation.

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Detalles Bibliográficos
Autores principales: Wenbin Wei, Jessica L. Faubel, Hemaa Selvakumar, Daniel T. Kovari, Joanna Tsao, Felipe Rivas, Amar T. Mohabir, Michelle Krecker, Elaheh Rahbar, Adam R. Hall, Michael A. Filler, Jennifer L. Washburn, Paul H. Weigel, Jennifer E. Curtis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/512ee6ef6392433884c3d7aba09c8777
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Descripción
Sumario:Polymer brushes are often used to functionalise surfaces. Here, the authors report on the creation of high-density, regenerating hyaluronan brushes using hyaluronan synthase enzymes which can be patterned by photo-deactivation and demonstrate biocompatibility and resistance to biofilm formation.