On the modulation and maintenance of hibernation in captive dwarf lemurs

Abstract In nature, photoperiod signals environmental seasonality and is a strong selective “zeitgeber” that synchronizes biological rhythms. For animals facing seasonal environmental challenges and energetic bottlenecks, daily torpor and hibernation are two metabolic strategies that can save energy...

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Autores principales:	Marina B. Blanco, Lydia K. Greene, Robert Schopler, Cathy V. Williams, Danielle Lynch, Jenna Browning, Kay Welser, Melanie Simmons, Peter H. Klopfer, Erin E. Ehmke
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5138ac6e88064aec82600c76d80a4917
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spelling	oai:doaj.org-article:5138ac6e88064aec82600c76d80a49172021-12-02T13:19:20ZOn the modulation and maintenance of hibernation in captive dwarf lemurs10.1038/s41598-021-84727-32045-2322https://doaj.org/article/5138ac6e88064aec82600c76d80a49172021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-84727-3https://doaj.org/toc/2045-2322Abstract In nature, photoperiod signals environmental seasonality and is a strong selective “zeitgeber” that synchronizes biological rhythms. For animals facing seasonal environmental challenges and energetic bottlenecks, daily torpor and hibernation are two metabolic strategies that can save energy. In the wild, the dwarf lemurs of Madagascar are obligate hibernators, hibernating between 3 and 7 months a year. In captivity, however, dwarf lemurs generally express torpor for periods far shorter than the hibernation season in Madagascar. We investigated whether fat-tailed dwarf lemurs (Cheirogaleus medius) housed at the Duke Lemur Center (DLC) could hibernate, by subjecting 8 individuals to husbandry conditions more in accord with those in Madagascar, including alternating photoperiods, low ambient temperatures, and food restriction. All dwarf lemurs displayed daily and multiday torpor bouts, including bouts lasting ~ 11 days. Ambient temperature was the greatest predictor of torpor bout duration, and food ingestion and night length also played a role. Unlike their wild counterparts, who rarely leave their hibernacula and do not feed during hibernation, DLC dwarf lemurs sporadically moved and ate. While demonstrating that captive dwarf lemurs are physiologically capable of hibernation, we argue that facilitating their hibernation serves both husbandry and research goals: first, it enables lemurs to express the biphasic phenotypes (fattening and fat depletion) that are characteristic of their wild conspecifics; second, by “renaturalizing” dwarf lemurs in captivity, they will emerge a better model for understanding both metabolic extremes in primates generally and metabolic disorders in humans specifically.Marina B. BlancoLydia K. GreeneRobert SchoplerCathy V. WilliamsDanielle LynchJenna BrowningKay WelserMelanie SimmonsPeter H. KlopferErin E. EhmkeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Marina B. Blanco Lydia K. Greene Robert Schopler Cathy V. Williams Danielle Lynch Jenna Browning Kay Welser Melanie Simmons Peter H. Klopfer Erin E. Ehmke On the modulation and maintenance of hibernation in captive dwarf lemurs
description	Abstract In nature, photoperiod signals environmental seasonality and is a strong selective “zeitgeber” that synchronizes biological rhythms. For animals facing seasonal environmental challenges and energetic bottlenecks, daily torpor and hibernation are two metabolic strategies that can save energy. In the wild, the dwarf lemurs of Madagascar are obligate hibernators, hibernating between 3 and 7 months a year. In captivity, however, dwarf lemurs generally express torpor for periods far shorter than the hibernation season in Madagascar. We investigated whether fat-tailed dwarf lemurs (Cheirogaleus medius) housed at the Duke Lemur Center (DLC) could hibernate, by subjecting 8 individuals to husbandry conditions more in accord with those in Madagascar, including alternating photoperiods, low ambient temperatures, and food restriction. All dwarf lemurs displayed daily and multiday torpor bouts, including bouts lasting ~ 11 days. Ambient temperature was the greatest predictor of torpor bout duration, and food ingestion and night length also played a role. Unlike their wild counterparts, who rarely leave their hibernacula and do not feed during hibernation, DLC dwarf lemurs sporadically moved and ate. While demonstrating that captive dwarf lemurs are physiologically capable of hibernation, we argue that facilitating their hibernation serves both husbandry and research goals: first, it enables lemurs to express the biphasic phenotypes (fattening and fat depletion) that are characteristic of their wild conspecifics; second, by “renaturalizing” dwarf lemurs in captivity, they will emerge a better model for understanding both metabolic extremes in primates generally and metabolic disorders in humans specifically.
format	article
author	Marina B. Blanco Lydia K. Greene Robert Schopler Cathy V. Williams Danielle Lynch Jenna Browning Kay Welser Melanie Simmons Peter H. Klopfer Erin E. Ehmke
author_facet	Marina B. Blanco Lydia K. Greene Robert Schopler Cathy V. Williams Danielle Lynch Jenna Browning Kay Welser Melanie Simmons Peter H. Klopfer Erin E. Ehmke
author_sort	Marina B. Blanco
title	On the modulation and maintenance of hibernation in captive dwarf lemurs
title_short	On the modulation and maintenance of hibernation in captive dwarf lemurs
title_full	On the modulation and maintenance of hibernation in captive dwarf lemurs
title_fullStr	On the modulation and maintenance of hibernation in captive dwarf lemurs
title_full_unstemmed	On the modulation and maintenance of hibernation in captive dwarf lemurs
title_sort	on the modulation and maintenance of hibernation in captive dwarf lemurs
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5138ac6e88064aec82600c76d80a4917
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On the modulation and maintenance of hibernation in captive dwarf lemurs

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