Systematic screening of generic drugs for progressive multiple sclerosis identifies clomipramine as a promising therapeutic
Progressive multiple sclerosis is an inflammatory and degenerative disease of the central nervous system, for which effective treatment is lacking. The authors carry out a screen to identify orally available generic medications, and show that the antidepressant clomipramine reduces pathology in mous...
Guardado en:
Autores principales: | Simon Faissner, Manoj Mishra, Deepak K. Kaushik, Jianxiong Wang, Yan Fan, Claudia Silva, Gail Rauw, Luanne Metz, Marcus Koch, V. Wee Yong |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/5138f03dd48544af82faa46f48eca8b2 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Chronic clomipramine treatment reverses core symptom of depression in subordinate tree shrews.
por: Jing Wang, et al.
Publicado: (2013) -
Plant-Derived Compounds as Promising Therapeutics for Vitiligo
por: Yaobin Pang, et al.
Publicado: (2021) -
Design and screening of a glial cell-specific, cell penetrating peptide for therapeutic applications in multiple sclerosis.
por: Corey Heffernan, et al.
Publicado: (2012) -
Determination of therapeutic equivalence of generic products of gentamicin in the neutropenic mouse thigh infection model.
por: Andres F Zuluaga, et al.
Publicado: (2010) -
Neoechinulins: Molecular, cellular, and functional attributes as promising therapeutics against cancer and other human diseases
por: Sicon Mitra, et al.
Publicado: (2022)