Time until treatment initiation is associated with catheter survival in peritoneal dialysis-related peritonitis

Abstract For peritonitis, a serious complication of peritoneal dialysis (PD), we investigated the relation between duration from the sign (PD effluent abnormalities) to treatment with appropriate antibiotics (ST time) and catheter removal. For 62 PD hospital patients, data of PD-related peritonitis...

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Autores principales:	Rikako Oki, Shiho Tsuji, Yoshifumi Hamasaki, Yohei Komaru, Yoshihisa Miyamoto, Ryo Matsuura, Daisuke Yamada, Kent Doi, Haruki Kume, Masaomi Nangaku
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5140c7555fbb4a9e99dd6adc08175d77
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spelling	oai:doaj.org-article:5140c7555fbb4a9e99dd6adc08175d772021-12-02T17:04:36ZTime until treatment initiation is associated with catheter survival in peritoneal dialysis-related peritonitis10.1038/s41598-021-86071-y2045-2322https://doaj.org/article/5140c7555fbb4a9e99dd6adc08175d772021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-86071-yhttps://doaj.org/toc/2045-2322Abstract For peritonitis, a serious complication of peritoneal dialysis (PD), we investigated the relation between duration from the sign (PD effluent abnormalities) to treatment with appropriate antibiotics (ST time) and catheter removal. For 62 PD hospital patients, data of PD-related peritonitis (n = 109) were collected retrospectively. We examined ST time and PD catheter removal times using univariate and multivariate analyses. The catheter removal rate in the delayed ST time group (≥ 24 h) was higher than that in early ST time group (< 24 h) (38 vs. 16%, p = 0.02). Concomitant tunnel infection and delayed ST time were associated with catheter removal (OR [95% CI] 32.3 [3.15–329] and 3.52 [1.11–11.1]). Rates of catheter removal and re-development of peritonitis within 1 month after starting treatment were higher in the delayed ST time group (p = 0.02). PD duration at peritonitis and the first peritonitis episode were associated with delayed ST time (1.02 [1.00–1.04] and 3.42 [1.09–10.7]). Significant association was found between PD catheter removal and the start of treatment more than 24 h after appearance of abnormal effluent. Education for patients about prompt visitation at the onset of peritonitis with long PD duration might improve outcomes.Rikako OkiShiho TsujiYoshifumi HamasakiYohei KomaruYoshihisa MiyamotoRyo MatsuuraDaisuke YamadaKent DoiHaruki KumeMasaomi NangakuNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Rikako Oki Shiho Tsuji Yoshifumi Hamasaki Yohei Komaru Yoshihisa Miyamoto Ryo Matsuura Daisuke Yamada Kent Doi Haruki Kume Masaomi Nangaku Time until treatment initiation is associated with catheter survival in peritoneal dialysis-related peritonitis
description	Abstract For peritonitis, a serious complication of peritoneal dialysis (PD), we investigated the relation between duration from the sign (PD effluent abnormalities) to treatment with appropriate antibiotics (ST time) and catheter removal. For 62 PD hospital patients, data of PD-related peritonitis (n = 109) were collected retrospectively. We examined ST time and PD catheter removal times using univariate and multivariate analyses. The catheter removal rate in the delayed ST time group (≥ 24 h) was higher than that in early ST time group (< 24 h) (38 vs. 16%, p = 0.02). Concomitant tunnel infection and delayed ST time were associated with catheter removal (OR [95% CI] 32.3 [3.15–329] and 3.52 [1.11–11.1]). Rates of catheter removal and re-development of peritonitis within 1 month after starting treatment were higher in the delayed ST time group (p = 0.02). PD duration at peritonitis and the first peritonitis episode were associated with delayed ST time (1.02 [1.00–1.04] and 3.42 [1.09–10.7]). Significant association was found between PD catheter removal and the start of treatment more than 24 h after appearance of abnormal effluent. Education for patients about prompt visitation at the onset of peritonitis with long PD duration might improve outcomes.
format	article
author	Rikako Oki Shiho Tsuji Yoshifumi Hamasaki Yohei Komaru Yoshihisa Miyamoto Ryo Matsuura Daisuke Yamada Kent Doi Haruki Kume Masaomi Nangaku
author_facet	Rikako Oki Shiho Tsuji Yoshifumi Hamasaki Yohei Komaru Yoshihisa Miyamoto Ryo Matsuura Daisuke Yamada Kent Doi Haruki Kume Masaomi Nangaku
author_sort	Rikako Oki
title	Time until treatment initiation is associated with catheter survival in peritoneal dialysis-related peritonitis
title_short	Time until treatment initiation is associated with catheter survival in peritoneal dialysis-related peritonitis
title_full	Time until treatment initiation is associated with catheter survival in peritoneal dialysis-related peritonitis
title_fullStr	Time until treatment initiation is associated with catheter survival in peritoneal dialysis-related peritonitis
title_full_unstemmed	Time until treatment initiation is associated with catheter survival in peritoneal dialysis-related peritonitis
title_sort	time until treatment initiation is associated with catheter survival in peritoneal dialysis-related peritonitis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5140c7555fbb4a9e99dd6adc08175d77
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Time until treatment initiation is associated with catheter survival in peritoneal dialysis-related peritonitis

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