Pd(II)-catalysed meta-C–H functionalizations of benzoic acid derivatives

While directed ortho-metalation is a well-established protocol, meta-functionalisation of aromatic groups is more challenging. Here, the authors report a directed meta-C-H functionalisation of benzoic acid derivatives, using a nitrile-based sulfonamide directing group.

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Detalles Bibliográficos
Autores principales: Shangda Li, Lei Cai, Huafang Ji, Long Yang, Gang Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/5141b73389aa4bc68608e8dbb1e40d06
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