Checkpoint blockade and nanosonosensitizer-augmented noninvasive sonodynamic therapy combination reduces tumour growth and metastases in mice

Immunotherapy for the treatment of cancer can be complicated by side effects and poor efficacy. Here, the authors use a nanoparticle-based approach in combination with a TLR7 agonist and sonodynamic therapy, and find that when used together with anti-PD-L1, tumour formation and metastases are impact...

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Autores principales: Wenwen Yue, Liang Chen, Luodan Yu, Bangguo Zhou, Haohao Yin, Weiwei Ren, Chang Liu, Lehang Guo, Yifeng Zhang, Liping Sun, Kun Zhang, Huixiong Xu, Yu Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/514612188b274ea7bd139a20fa716512
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