Glycogen metabolism regulates macrophage-mediated acute inflammatory responses

Glycogen can be metabolized via glycogenolysis and the pentose phosphate pathway as well as into the production of UDP glucose, which when secreted can bind the P2Y14 receptor. Here the authors show how these glycogen metabolism pathways contribute to proinflammatory macrophage activation and suscep...

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Autores principales:	Jingwei Ma, Keke Wei, Junwei Liu, Ke Tang, Huafeng Zhang, Liyan Zhu, Jie Chen, Fei Li, Pingwei Xu, Jincheng Liu, Haiqing Fang, Liang Tang, Dianheng Wang, Liping Zeng, Weiwei Sun, Jing Xie, Yuying Liu, Bo Huang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5147ac64c2054a77adfffdcb6f32df95
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spelling	oai:doaj.org-article:5147ac64c2054a77adfffdcb6f32df952021-12-02T14:40:42ZGlycogen metabolism regulates macrophage-mediated acute inflammatory responses10.1038/s41467-020-15636-82041-1723https://doaj.org/article/5147ac64c2054a77adfffdcb6f32df952020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15636-8https://doaj.org/toc/2041-1723Glycogen can be metabolized via glycogenolysis and the pentose phosphate pathway as well as into the production of UDP glucose, which when secreted can bind the P2Y14 receptor. Here the authors show how these glycogen metabolism pathways contribute to proinflammatory macrophage activation and susceptibility to sepsis.Jingwei MaKeke WeiJunwei LiuKe TangHuafeng ZhangLiyan ZhuJie ChenFei LiPingwei XuJie ChenJincheng LiuHaiqing FangLiang TangDianheng WangLiping ZengWeiwei SunJing XieYuying LiuBo HuangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jingwei Ma Keke Wei Junwei Liu Ke Tang Huafeng Zhang Liyan Zhu Jie Chen Fei Li Pingwei Xu Jie Chen Jincheng Liu Haiqing Fang Liang Tang Dianheng Wang Liping Zeng Weiwei Sun Jing Xie Yuying Liu Bo Huang Glycogen metabolism regulates macrophage-mediated acute inflammatory responses
description	Glycogen can be metabolized via glycogenolysis and the pentose phosphate pathway as well as into the production of UDP glucose, which when secreted can bind the P2Y14 receptor. Here the authors show how these glycogen metabolism pathways contribute to proinflammatory macrophage activation and susceptibility to sepsis.
format	article
author	Jingwei Ma Keke Wei Junwei Liu Ke Tang Huafeng Zhang Liyan Zhu Jie Chen Fei Li Pingwei Xu Jie Chen Jincheng Liu Haiqing Fang Liang Tang Dianheng Wang Liping Zeng Weiwei Sun Jing Xie Yuying Liu Bo Huang
author_facet	Jingwei Ma Keke Wei Junwei Liu Ke Tang Huafeng Zhang Liyan Zhu Jie Chen Fei Li Pingwei Xu Jie Chen Jincheng Liu Haiqing Fang Liang Tang Dianheng Wang Liping Zeng Weiwei Sun Jing Xie Yuying Liu Bo Huang
author_sort	Jingwei Ma
title	Glycogen metabolism regulates macrophage-mediated acute inflammatory responses
title_short	Glycogen metabolism regulates macrophage-mediated acute inflammatory responses
title_full	Glycogen metabolism regulates macrophage-mediated acute inflammatory responses
title_fullStr	Glycogen metabolism regulates macrophage-mediated acute inflammatory responses
title_full_unstemmed	Glycogen metabolism regulates macrophage-mediated acute inflammatory responses
title_sort	glycogen metabolism regulates macrophage-mediated acute inflammatory responses
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/5147ac64c2054a77adfffdcb6f32df95
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Glycogen metabolism regulates macrophage-mediated acute inflammatory responses

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