Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms

Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms

Abstract Aminoacyl-tRNA synthetases (aaRSs) charge tRNAs with their cognate amino acid, an essential precursor step to loading of charged tRNAs onto the ribosome and addition of the amino acid to the growing polypeptide chain during protein synthesis. Because of this important biological function, a...

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Autores principales: Spencer O. Moen, Thomas E. Edwards, David M. Dranow, Matthew C. Clifton, Banumathi Sankaran, Wesley C. Van Voorhis, Amit Sharma, Colin Manoil, Bart L. Staker, Peter J. Myler, Donald D. Lorimer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/514875561f484af5b0d951c78c79f7d3
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