Comparison of three criteria for potentially inappropriate medications in Chinese older adults

Zhuo Ma,1,* Caixia Zhang,1,2,* Xiangli Cui,1 Lihong Liu1 1Pharmacy Department of Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China; 2Pharmacy Department of Civil Aviation General Hospital, Beijing, China *These authors contributed equally to this work Objectives: This study a...

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Autores principales:	Ma Z, Zhang C, Cui X, Liu L
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	potentially inappropriate medication Beers STOPP criteria of potentially inappropriate medications for older adults in China polypharmacy Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/51490d7641c8405ca89f295e63f60cec
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spelling	oai:doaj.org-article:51490d7641c8405ca89f295e63f60cec2021-12-02T02:40:06ZComparison of three criteria for potentially inappropriate medications in Chinese older adults1178-1998https://doaj.org/article/51490d7641c8405ca89f295e63f60cec2018-12-01T00:00:00Zhttps://www.dovepress.com/comparison-of-three-criteria-for-potentially-inappropriate-medications-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Zhuo Ma,1,* Caixia Zhang,1,2,* Xiangli Cui,1 Lihong Liu1 1Pharmacy Department of Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China; 2Pharmacy Department of Civil Aviation General Hospital, Beijing, China *These authors contributed equally to this work Objectives: This study aimed to compare the prevalence of potentially inappropriate medications (PIMs) among Chinese aged patients using the Beers criteria of 2015, the Screening Tool of Older Persons’ Prescriptions (STOPP) of 2014 and the criteria of PIMs for older adults in China (Chinese criteria), and to identify the correlates of the PIMs’ use. Methods: A retrospective, cross-sectional study was conducted among geriatric patients at Beijing Chao-Yang Hospital between January 2018 and March 2018. Three criteria (the Beers criteria of 2015, the STOPP criteria of 2014 and the Chinese criteria) were used to detect PIMs. A multivariate logistic regression analysis was carried out to determine factors associated with the use of PIMs. Leading PIMs for each set of criteria were also listed. The concordance among the three PIM criteria was calculated using kappa tests. Results: Totally, 863 inpatients aged ≥65 years were included. The prevalence of patients receiving at least one PIM was 80.2%, 58.1% and 44.0% according to the Chinese criteria, 2015 Beers criteria and 2014 STOPP criteria, respectively. The Beers and the STOPP criteria indicated a moderate coherence, whereas the Chinese criteria showed poor concordance with the other two criteria. Proton-pump inhibitors in the Beers and STOPP criteria and clopidogrel in the PIM-Chinese accounted for most leading PIMs. The most important factor associated with PIM use by all three sets of criteria was the number of prescribed medications. Conclusion: Data showed a high PIM prevalence among older adults in China, which was associated with the number of prescribed medications. The Chinese criteria had the highest detection rate but a poor concordance with the Beers and STOPP criteria (P<0.001). Keywords: elderly, hospitalized, Beers criteria, STOPP criteria, Chinese criteria, polypharmacyMa ZZhang CCui XLiu LDove Medical Pressarticlepotentially inappropriate medicationBeersSTOPPcriteria of potentially inappropriate medications for older adults in ChinapolypharmacyGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 14, Pp 65-72 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	potentially inappropriate medication Beers STOPP criteria of potentially inappropriate medications for older adults in China polypharmacy Geriatrics RC952-954.6
spellingShingle	potentially inappropriate medication Beers STOPP criteria of potentially inappropriate medications for older adults in China polypharmacy Geriatrics RC952-954.6 Ma Z Zhang C Cui X Liu L Comparison of three criteria for potentially inappropriate medications in Chinese older adults
description	Zhuo Ma,1,* Caixia Zhang,1,2,* Xiangli Cui,1 Lihong Liu1 1Pharmacy Department of Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China; 2Pharmacy Department of Civil Aviation General Hospital, Beijing, China *These authors contributed equally to this work Objectives: This study aimed to compare the prevalence of potentially inappropriate medications (PIMs) among Chinese aged patients using the Beers criteria of 2015, the Screening Tool of Older Persons’ Prescriptions (STOPP) of 2014 and the criteria of PIMs for older adults in China (Chinese criteria), and to identify the correlates of the PIMs’ use. Methods: A retrospective, cross-sectional study was conducted among geriatric patients at Beijing Chao-Yang Hospital between January 2018 and March 2018. Three criteria (the Beers criteria of 2015, the STOPP criteria of 2014 and the Chinese criteria) were used to detect PIMs. A multivariate logistic regression analysis was carried out to determine factors associated with the use of PIMs. Leading PIMs for each set of criteria were also listed. The concordance among the three PIM criteria was calculated using kappa tests. Results: Totally, 863 inpatients aged ≥65 years were included. The prevalence of patients receiving at least one PIM was 80.2%, 58.1% and 44.0% according to the Chinese criteria, 2015 Beers criteria and 2014 STOPP criteria, respectively. The Beers and the STOPP criteria indicated a moderate coherence, whereas the Chinese criteria showed poor concordance with the other two criteria. Proton-pump inhibitors in the Beers and STOPP criteria and clopidogrel in the PIM-Chinese accounted for most leading PIMs. The most important factor associated with PIM use by all three sets of criteria was the number of prescribed medications. Conclusion: Data showed a high PIM prevalence among older adults in China, which was associated with the number of prescribed medications. The Chinese criteria had the highest detection rate but a poor concordance with the Beers and STOPP criteria (P<0.001). Keywords: elderly, hospitalized, Beers criteria, STOPP criteria, Chinese criteria, polypharmacy
format	article
author	Ma Z Zhang C Cui X Liu L
author_facet	Ma Z Zhang C Cui X Liu L
author_sort	Ma Z
title	Comparison of three criteria for potentially inappropriate medications in Chinese older adults
title_short	Comparison of three criteria for potentially inappropriate medications in Chinese older adults
title_full	Comparison of three criteria for potentially inappropriate medications in Chinese older adults
title_fullStr	Comparison of three criteria for potentially inappropriate medications in Chinese older adults
title_full_unstemmed	Comparison of three criteria for potentially inappropriate medications in Chinese older adults
title_sort	comparison of three criteria for potentially inappropriate medications in chinese older adults
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/51490d7641c8405ca89f295e63f60cec
work_keys_str_mv	AT maz comparisonofthreecriteriaforpotentiallyinappropriatemedicationsinchineseolderadults AT zhangc comparisonofthreecriteriaforpotentiallyinappropriatemedicationsinchineseolderadults AT cuix comparisonofthreecriteriaforpotentiallyinappropriatemedicationsinchineseolderadults AT liul comparisonofthreecriteriaforpotentiallyinappropriatemedicationsinchineseolderadults
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Comparison of three criteria for potentially inappropriate medications in Chinese older adults

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