Trajectories of quality of life among Chinese patients diagnosed with nasopharynegeal cancer.

<h4>Objective</h4>This secondary longitudinal analysis describes distinct quality of life trajectories during eight months of radiation therapy (RT) among patients with nasopharyngeal cancer (NPC) and examines factors differentiating these trajectories.<h4>Methods</h4>253 Chi...

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Autores principales:	Wendy W T Lam, Michelle Ye, Richard Fielding
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/5155ec8bfdd7442c85fe7c8dcd87477f
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spelling	oai:doaj.org-article:5155ec8bfdd7442c85fe7c8dcd87477f2021-11-18T07:05:19ZTrajectories of quality of life among Chinese patients diagnosed with nasopharynegeal cancer.1932-620310.1371/journal.pone.0044022https://doaj.org/article/5155ec8bfdd7442c85fe7c8dcd87477f2012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23028484/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Objective</h4>This secondary longitudinal analysis describes distinct quality of life trajectories during eight months of radiation therapy (RT) among patients with nasopharyngeal cancer (NPC) and examines factors differentiating these trajectories.<h4>Methods</h4>253 Chinese patients with NPC scheduled for RT were assessed at pre-treatment, and 4 months and 8 months later on QoL (Chinese version of the FACT-G), optimism, pain, eating function, and patient satisfaction. Latent growth mixture modelling identified different trajectories within each of four QoL domains: Physical, Emotional, Social/family, and Functional well-being. Multinomial logistic regression compared optimism, pain, eating function, and patient satisfaction by trajectories adjusted for demographic and medical characteristics.<h4>Results</h4>We identified three distinct trajectories for physical and emotional QoL domains, four trajectories for social/family, and two trajectories for functional domains. Within each domain most patients (physical (77%), emotional (85%), social/family (55%) and functional (63%)) experienced relatively stable high levels of well-being over the 8-month period. Different Physical trajectory patterns were predicted by pain and optimism, whereas for Emotion-domain trajectories pain, optimism, eating enjoyment, patient satisfaction with information, and gender were predictive. Age, appetite, optimism, martial status, and household income predicted Social/family trajectories; household income, eating enjoyment, optimism, and patient satisfaction with information predicted Functional trajectories.<h4>Conclusion</h4>Most patients with NPC showed high stable QoL during radiotherapy. Optimism predicted good QoL. Symptom impacts varied by QoL domain. Information satisfaction was protective in emotional and functional well-being, reflecting the importance in helping patients to establish a realistic expectation of treatment impacts.Wendy W T LamMichelle YeRichard FieldingPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 9, p e44022 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Wendy W T Lam Michelle Ye Richard Fielding Trajectories of quality of life among Chinese patients diagnosed with nasopharynegeal cancer.
description	<h4>Objective</h4>This secondary longitudinal analysis describes distinct quality of life trajectories during eight months of radiation therapy (RT) among patients with nasopharyngeal cancer (NPC) and examines factors differentiating these trajectories.<h4>Methods</h4>253 Chinese patients with NPC scheduled for RT were assessed at pre-treatment, and 4 months and 8 months later on QoL (Chinese version of the FACT-G), optimism, pain, eating function, and patient satisfaction. Latent growth mixture modelling identified different trajectories within each of four QoL domains: Physical, Emotional, Social/family, and Functional well-being. Multinomial logistic regression compared optimism, pain, eating function, and patient satisfaction by trajectories adjusted for demographic and medical characteristics.<h4>Results</h4>We identified three distinct trajectories for physical and emotional QoL domains, four trajectories for social/family, and two trajectories for functional domains. Within each domain most patients (physical (77%), emotional (85%), social/family (55%) and functional (63%)) experienced relatively stable high levels of well-being over the 8-month period. Different Physical trajectory patterns were predicted by pain and optimism, whereas for Emotion-domain trajectories pain, optimism, eating enjoyment, patient satisfaction with information, and gender were predictive. Age, appetite, optimism, martial status, and household income predicted Social/family trajectories; household income, eating enjoyment, optimism, and patient satisfaction with information predicted Functional trajectories.<h4>Conclusion</h4>Most patients with NPC showed high stable QoL during radiotherapy. Optimism predicted good QoL. Symptom impacts varied by QoL domain. Information satisfaction was protective in emotional and functional well-being, reflecting the importance in helping patients to establish a realistic expectation of treatment impacts.
format	article
author	Wendy W T Lam Michelle Ye Richard Fielding
author_facet	Wendy W T Lam Michelle Ye Richard Fielding
author_sort	Wendy W T Lam
title	Trajectories of quality of life among Chinese patients diagnosed with nasopharynegeal cancer.
title_short	Trajectories of quality of life among Chinese patients diagnosed with nasopharynegeal cancer.
title_full	Trajectories of quality of life among Chinese patients diagnosed with nasopharynegeal cancer.
title_fullStr	Trajectories of quality of life among Chinese patients diagnosed with nasopharynegeal cancer.
title_full_unstemmed	Trajectories of quality of life among Chinese patients diagnosed with nasopharynegeal cancer.
title_sort	trajectories of quality of life among chinese patients diagnosed with nasopharynegeal cancer.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/5155ec8bfdd7442c85fe7c8dcd87477f
work_keys_str_mv	AT wendywtlam trajectoriesofqualityoflifeamongchinesepatientsdiagnosedwithnasopharynegealcancer AT michelleye trajectoriesofqualityoflifeamongchinesepatientsdiagnosedwithnasopharynegealcancer AT richardfielding trajectoriesofqualityoflifeamongchinesepatientsdiagnosedwithnasopharynegealcancer
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Trajectories of quality of life among Chinese patients diagnosed with nasopharynegeal cancer.

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