Addressing MRSA infection and antibacterial resistance with peptoid polymers
Antibiotic resistance is a major issue in medicine and new antimicrobials for treating resistant infection are needed. Here, the authors report on antibacterial peptoid polymers, prepared via NNCA ring-opening polymerization, demonstrating antibacterial function against MRSA in vitro and in in vivo...
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Nature Portfolio
2021
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Acceso en línea: | https://doaj.org/article/5156e8b924224ead908f29cd19d0cd20 |
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oai:doaj.org-article:5156e8b924224ead908f29cd19d0cd202021-12-02T17:13:18ZAddressing MRSA infection and antibacterial resistance with peptoid polymers10.1038/s41467-021-26221-y2041-1723https://doaj.org/article/5156e8b924224ead908f29cd19d0cd202021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26221-yhttps://doaj.org/toc/2041-1723Antibiotic resistance is a major issue in medicine and new antimicrobials for treating resistant infection are needed. Here, the authors report on antibacterial peptoid polymers, prepared via NNCA ring-opening polymerization, demonstrating antibacterial function against MRSA in vitro and in in vivo infection models.Jiayang XieMin ZhouYuxin QianZihao CongSheng ChenWenjing ZhangWeinan JiangChengzhi DaiNing ShaoZhemin JiJingcheng ZouXimian XiaoLongqiang LiuMinzhang ChenJin LiRunhui LiuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Jiayang Xie Min Zhou Yuxin Qian Zihao Cong Sheng Chen Wenjing Zhang Weinan Jiang Chengzhi Dai Ning Shao Zhemin Ji Jingcheng Zou Ximian Xiao Longqiang Liu Minzhang Chen Jin Li Runhui Liu Addressing MRSA infection and antibacterial resistance with peptoid polymers |
description |
Antibiotic resistance is a major issue in medicine and new antimicrobials for treating resistant infection are needed. Here, the authors report on antibacterial peptoid polymers, prepared via NNCA ring-opening polymerization, demonstrating antibacterial function against MRSA in vitro and in in vivo infection models. |
format |
article |
author |
Jiayang Xie Min Zhou Yuxin Qian Zihao Cong Sheng Chen Wenjing Zhang Weinan Jiang Chengzhi Dai Ning Shao Zhemin Ji Jingcheng Zou Ximian Xiao Longqiang Liu Minzhang Chen Jin Li Runhui Liu |
author_facet |
Jiayang Xie Min Zhou Yuxin Qian Zihao Cong Sheng Chen Wenjing Zhang Weinan Jiang Chengzhi Dai Ning Shao Zhemin Ji Jingcheng Zou Ximian Xiao Longqiang Liu Minzhang Chen Jin Li Runhui Liu |
author_sort |
Jiayang Xie |
title |
Addressing MRSA infection and antibacterial resistance with peptoid polymers |
title_short |
Addressing MRSA infection and antibacterial resistance with peptoid polymers |
title_full |
Addressing MRSA infection and antibacterial resistance with peptoid polymers |
title_fullStr |
Addressing MRSA infection and antibacterial resistance with peptoid polymers |
title_full_unstemmed |
Addressing MRSA infection and antibacterial resistance with peptoid polymers |
title_sort |
addressing mrsa infection and antibacterial resistance with peptoid polymers |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/5156e8b924224ead908f29cd19d0cd20 |
work_keys_str_mv |
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1718381318098649088 |