Addressing MRSA infection and antibacterial resistance with peptoid polymers

Antibiotic resistance is a major issue in medicine and new antimicrobials for treating resistant infection are needed. Here, the authors report on antibacterial peptoid polymers, prepared via NNCA ring-opening polymerization, demonstrating antibacterial function against MRSA in vitro and in in vivo...

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Autores principales: Jiayang Xie, Min Zhou, Yuxin Qian, Zihao Cong, Sheng Chen, Wenjing Zhang, Weinan Jiang, Chengzhi Dai, Ning Shao, Zhemin Ji, Jingcheng Zou, Ximian Xiao, Longqiang Liu, Minzhang Chen, Jin Li, Runhui Liu
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5156e8b924224ead908f29cd19d0cd20
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spelling oai:doaj.org-article:5156e8b924224ead908f29cd19d0cd202021-12-02T17:13:18ZAddressing MRSA infection and antibacterial resistance with peptoid polymers10.1038/s41467-021-26221-y2041-1723https://doaj.org/article/5156e8b924224ead908f29cd19d0cd202021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26221-yhttps://doaj.org/toc/2041-1723Antibiotic resistance is a major issue in medicine and new antimicrobials for treating resistant infection are needed. Here, the authors report on antibacterial peptoid polymers, prepared via NNCA ring-opening polymerization, demonstrating antibacterial function against MRSA in vitro and in in vivo infection models.Jiayang XieMin ZhouYuxin QianZihao CongSheng ChenWenjing ZhangWeinan JiangChengzhi DaiNing ShaoZhemin JiJingcheng ZouXimian XiaoLongqiang LiuMinzhang ChenJin LiRunhui LiuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jiayang Xie
Min Zhou
Yuxin Qian
Zihao Cong
Sheng Chen
Wenjing Zhang
Weinan Jiang
Chengzhi Dai
Ning Shao
Zhemin Ji
Jingcheng Zou
Ximian Xiao
Longqiang Liu
Minzhang Chen
Jin Li
Runhui Liu
Addressing MRSA infection and antibacterial resistance with peptoid polymers
description Antibiotic resistance is a major issue in medicine and new antimicrobials for treating resistant infection are needed. Here, the authors report on antibacterial peptoid polymers, prepared via NNCA ring-opening polymerization, demonstrating antibacterial function against MRSA in vitro and in in vivo infection models.
format article
author Jiayang Xie
Min Zhou
Yuxin Qian
Zihao Cong
Sheng Chen
Wenjing Zhang
Weinan Jiang
Chengzhi Dai
Ning Shao
Zhemin Ji
Jingcheng Zou
Ximian Xiao
Longqiang Liu
Minzhang Chen
Jin Li
Runhui Liu
author_facet Jiayang Xie
Min Zhou
Yuxin Qian
Zihao Cong
Sheng Chen
Wenjing Zhang
Weinan Jiang
Chengzhi Dai
Ning Shao
Zhemin Ji
Jingcheng Zou
Ximian Xiao
Longqiang Liu
Minzhang Chen
Jin Li
Runhui Liu
author_sort Jiayang Xie
title Addressing MRSA infection and antibacterial resistance with peptoid polymers
title_short Addressing MRSA infection and antibacterial resistance with peptoid polymers
title_full Addressing MRSA infection and antibacterial resistance with peptoid polymers
title_fullStr Addressing MRSA infection and antibacterial resistance with peptoid polymers
title_full_unstemmed Addressing MRSA infection and antibacterial resistance with peptoid polymers
title_sort addressing mrsa infection and antibacterial resistance with peptoid polymers
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/5156e8b924224ead908f29cd19d0cd20
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