A protein of the metallo-hydrolase/oxidoreductase superfamily with both beta-lactamase and ribonuclease activity is linked with translation in giant viruses

Abstract Proteins with a metallo-beta-lactamase (MBL) fold have been largely studied in bacteria in the framework of resistance to beta-lactams, but their spectrum of activities is broader. We show here that the giant Tupanvirus also encodes a MBL fold-protein that has orthologs in other giant virus...

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Bibliographic Details
Main Authors: Philippe Colson, Lucile Pinault, Said Azza, Nicholas Armstrong, Eric Chabriere, Bernard La Scola, Pierre Pontarotti, Didier Raoult
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
R
Q
Online Access:https://doaj.org/article/516419e93f734da0b512404dcdd8e9e0
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