8q24 genetic variation and comprehensive haplotypes altering familial risk of prostate cancer

8q24 genetic variation and comprehensive haplotypes altering familial risk of prostate cancer

Inherited alterations of the 8q24 genomic locus are linked to cancer etiology. Here, the authors investigate hereditary prostate cancer to reveal ancestral risk-altering haplotypes, the sentinel genetic variants optimally predicting risk, and causal mutation candidates.

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Bibliographic Details
Main Authors: William D. Dupont, Joan P. Breyer, W. Dale Plummer, Sam S. Chang, Michael S. Cookson, Joseph A. Smith, University of Washington Center for Mendelian Genomics, Elizabeth E. Blue, Michael J. Bamshad, Jeffrey R. Smith
Format: article
Language:EN
Published: Nature Portfolio 2020
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Science
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Online Access:https://doaj.org/article/516b649d3bb74353b9d7764b84ffcce6
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Internet

https://doaj.org/article/516b649d3bb74353b9d7764b84ffcce6

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