Platelet Profile in Patients with Status Asmaticus in Kebumen

BACKGROUND: Asthma has been considered as type 1 hypersensitivity disease, but actually asthma involves a variety of inf lammatory factors. Based on pro-inf lammatory cells, asthma is classified into eosinophilic, non-eosinophilic, neutrophilic, and non-neutrophilic. Platelet plays a role in  pathop...

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Autores principales: Juwariyah Juwariyah, Adika Zhulhi Arjana, Ester Tri Rahayu, Linda Rosita, Mohammad Rozan Irfan
Formato: article
Lenguaje:EN
Publicado: Universitas Sultan Agung Semarang 2017
Materias:
mpv
pdw
pct
Acceso en línea:https://doaj.org/article/51758164696b44a3a2a303ac555d5fd0
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spelling oai:doaj.org-article:51758164696b44a3a2a303ac555d5fd02021-11-25T13:15:53ZPlatelet Profile in Patients with Status Asmaticus in Kebumen2085-15452339-093X10.26532/sainsmed.v8i2.1003https://doaj.org/article/51758164696b44a3a2a303ac555d5fd02017-10-01T00:00:00Zhttp://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/1003https://doaj.org/toc/2085-1545https://doaj.org/toc/2339-093XBACKGROUND: Asthma has been considered as type 1 hypersensitivity disease, but actually asthma involves a variety of inf lammatory factors. Based on pro-inf lammatory cells, asthma is classified into eosinophilic, non-eosinophilic, neutrophilic, and non-neutrophilic. Platelet plays a role in  pathophysiology of asthma through inf lammation. However, platelet profile in patients with asthma have not been established. OBJECTIVE: to determine the platelet indices of patients with status asmaticus of different phenotypes. METHODS: a cross-sectional study was conducted among a minimum sample size of 67 patients. Data were collected from medical records of patients in RSUD Kebumen. Platelet indices included mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT). RESULTS: There was no significant difference in the value of MPV and PDW in patients with eosinophilic and neutrophilic asthma (p> 0.05). But, there was a significant difference in PCT between the two groups (P <0.05) CONCLUSION: There was difference only in plateletcrit (PCT) between patients with eosinophilic and netrophilic asthma.Juwariyah JuwariyahAdika Zhulhi ArjanaEster Tri RahayuLinda RositaMohammad Rozan IrfanUniversitas Sultan Agung SemarangarticleasthmaplateletsmpvpdwpctMedicine (General)R5-920ENSains Medika, Vol 8, Iss 2 (2017)
institution DOAJ
collection DOAJ
language EN
topic asthma
platelets
mpv
pdw
pct
Medicine (General)
R5-920
spellingShingle asthma
platelets
mpv
pdw
pct
Medicine (General)
R5-920
Juwariyah Juwariyah
Adika Zhulhi Arjana
Ester Tri Rahayu
Linda Rosita
Mohammad Rozan Irfan
Platelet Profile in Patients with Status Asmaticus in Kebumen
description BACKGROUND: Asthma has been considered as type 1 hypersensitivity disease, but actually asthma involves a variety of inf lammatory factors. Based on pro-inf lammatory cells, asthma is classified into eosinophilic, non-eosinophilic, neutrophilic, and non-neutrophilic. Platelet plays a role in  pathophysiology of asthma through inf lammation. However, platelet profile in patients with asthma have not been established. OBJECTIVE: to determine the platelet indices of patients with status asmaticus of different phenotypes. METHODS: a cross-sectional study was conducted among a minimum sample size of 67 patients. Data were collected from medical records of patients in RSUD Kebumen. Platelet indices included mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT). RESULTS: There was no significant difference in the value of MPV and PDW in patients with eosinophilic and neutrophilic asthma (p> 0.05). But, there was a significant difference in PCT between the two groups (P <0.05) CONCLUSION: There was difference only in plateletcrit (PCT) between patients with eosinophilic and netrophilic asthma.
format article
author Juwariyah Juwariyah
Adika Zhulhi Arjana
Ester Tri Rahayu
Linda Rosita
Mohammad Rozan Irfan
author_facet Juwariyah Juwariyah
Adika Zhulhi Arjana
Ester Tri Rahayu
Linda Rosita
Mohammad Rozan Irfan
author_sort Juwariyah Juwariyah
title Platelet Profile in Patients with Status Asmaticus in Kebumen
title_short Platelet Profile in Patients with Status Asmaticus in Kebumen
title_full Platelet Profile in Patients with Status Asmaticus in Kebumen
title_fullStr Platelet Profile in Patients with Status Asmaticus in Kebumen
title_full_unstemmed Platelet Profile in Patients with Status Asmaticus in Kebumen
title_sort platelet profile in patients with status asmaticus in kebumen
publisher Universitas Sultan Agung Semarang
publishDate 2017
url https://doaj.org/article/51758164696b44a3a2a303ac555d5fd0
work_keys_str_mv AT juwariyahjuwariyah plateletprofileinpatientswithstatusasmaticusinkebumen
AT adikazhulhiarjana plateletprofileinpatientswithstatusasmaticusinkebumen
AT estertrirahayu plateletprofileinpatientswithstatusasmaticusinkebumen
AT lindarosita plateletprofileinpatientswithstatusasmaticusinkebumen
AT mohammadrozanirfan plateletprofileinpatientswithstatusasmaticusinkebumen
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