A synthetic peptide library for benchmarking crosslinking-mass spectrometry search engines for proteins and protein complexes
Validating crosslinking-mass spectrometry workflows is hampered by the lack of a ground truth to assess the robustness of the crosslink identifications. Here, the authors present a synthetic library of crosslinked peptides, enabling unambiguous discrimination of correct and incorrect crosslink ident...
Guardado en:
Autores principales: | Rebecca Beveridge, Johannes Stadlmann, Josef M. Penninger, Karl Mechtler |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/51759c8d309249a39e0926ce4db32372 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Reliable identification of protein-protein interactions by crosslinking mass spectrometry
por: Swantje Lenz, et al.
Publicado: (2021) -
Evaluation of mass spectrometry MS/MS spectra for the presence of isopeptide crosslinked peptides.
por: Lawrence M Schopfer, et al.
Publicado: (2021) -
Chromatogram libraries improve peptide detection and quantification by data independent acquisition mass spectrometry
por: Brian C. Searle, et al.
Publicado: (2018) -
Retention time prediction using neural networks increases identifications in crosslinking mass spectrometry
por: Sven H. Giese, et al.
Publicado: (2021) -
Ultrafast enzymatic digestion of proteins by microdroplet mass spectrometry
por: Xiaoqin Zhong, et al.
Publicado: (2020)