Detection of Cytosolic <italic toggle="yes">Shigella flexneri</italic> via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility
ABSTRACT Dynamin-like guanylate binding proteins (GBPs) are gamma interferon (IFN-γ)-inducible host defense proteins that can associate with cytosol-invading bacterial pathogens. Mouse GBPs promote the lytic destruction of targeted bacteria in the host cell cytosol, but the antimicrobial function of...
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| Main Authors: | , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2017
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| Subjects: | |
| Online Access: | https://doaj.org/article/51771ab8e9bf43aaa2843d2a7d4c7174 |
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