POLYMORPHISM OF ANGIOTENSIN II ALFA-GENE OF THE 1<sup>ST</sup> TYPE IN CHILDREN WITH SECONDARY HYPERTENSION
The article presents the results of genetic typing of blood samples of children with glomerulonephritis and congenital abnormalities of the urinary system with different levels of blood pressure by A1166C-polymorphism of gene AGTR1 by the method of polymerase chain reaction. Comparative frequency an...
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Scientific Сentre for Family Health and Human Reproduction Problems
2014
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oai:doaj.org-article:517ee1529dcd440c80907f199912176d2021-11-23T06:14:30ZPOLYMORPHISM OF ANGIOTENSIN II ALFA-GENE OF THE 1<sup>ST</sup> TYPE IN CHILDREN WITH SECONDARY HYPERTENSION2541-94202587-9596https://doaj.org/article/517ee1529dcd440c80907f199912176d2014-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1733https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The article presents the results of genetic typing of blood samples of children with glomerulonephritis and congenital abnormalities of the urinary system with different levels of blood pressure by A1166C-polymorphism of gene AGTR1 by the method of polymerase chain reaction. Comparative frequency analysis of genotypes (χ2 = 3,74; df = 5; p = 0,39) and alleles degrees of incidence (χ2 = 4,28; df = 5; p = 0,31) did not reveal statistically significant differences. Consequently, association of this polymorphism with secondary hypertension wasn't detected.L. I. KolesnikovaV. V. DolgikhT. A. AstakhovaV. V. AlbotE. V. BelyaevaScientific Сentre for Family Health and Human Reproduction Problemsarticlesecondary hypertensionagtr1 geneScienceQRUActa Biomedica Scientifica, Vol 0, Iss 2, Pp 32-35 (2014) |
| institution |
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| collection |
DOAJ |
| language |
RU |
| topic |
secondary hypertension agtr1 gene Science Q |
| spellingShingle |
secondary hypertension agtr1 gene Science Q L. I. Kolesnikova V. V. Dolgikh T. A. Astakhova V. V. Albot E. V. Belyaeva POLYMORPHISM OF ANGIOTENSIN II ALFA-GENE OF THE 1<sup>ST</sup> TYPE IN CHILDREN WITH SECONDARY HYPERTENSION |
| description |
The article presents the results of genetic typing of blood samples of children with glomerulonephritis and congenital abnormalities of the urinary system with different levels of blood pressure by A1166C-polymorphism of gene AGTR1 by the method of polymerase chain reaction. Comparative frequency analysis of genotypes (χ2 = 3,74; df = 5; p = 0,39) and alleles degrees of incidence (χ2 = 4,28; df = 5; p = 0,31) did not reveal statistically significant differences. Consequently, association of this polymorphism with secondary hypertension wasn't detected. |
| format |
article |
| author |
L. I. Kolesnikova V. V. Dolgikh T. A. Astakhova V. V. Albot E. V. Belyaeva |
| author_facet |
L. I. Kolesnikova V. V. Dolgikh T. A. Astakhova V. V. Albot E. V. Belyaeva |
| author_sort |
L. I. Kolesnikova |
| title |
POLYMORPHISM OF ANGIOTENSIN II ALFA-GENE OF THE 1<sup>ST</sup> TYPE IN CHILDREN WITH SECONDARY HYPERTENSION |
| title_short |
POLYMORPHISM OF ANGIOTENSIN II ALFA-GENE OF THE 1<sup>ST</sup> TYPE IN CHILDREN WITH SECONDARY HYPERTENSION |
| title_full |
POLYMORPHISM OF ANGIOTENSIN II ALFA-GENE OF THE 1<sup>ST</sup> TYPE IN CHILDREN WITH SECONDARY HYPERTENSION |
| title_fullStr |
POLYMORPHISM OF ANGIOTENSIN II ALFA-GENE OF THE 1<sup>ST</sup> TYPE IN CHILDREN WITH SECONDARY HYPERTENSION |
| title_full_unstemmed |
POLYMORPHISM OF ANGIOTENSIN II ALFA-GENE OF THE 1<sup>ST</sup> TYPE IN CHILDREN WITH SECONDARY HYPERTENSION |
| title_sort |
polymorphism of angiotensin ii alfa-gene of the 1<sup>st</sup> type in children with secondary hypertension |
| publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
| publishDate |
2014 |
| url |
https://doaj.org/article/517ee1529dcd440c80907f199912176d |
| work_keys_str_mv |
AT likolesnikova polymorphismofangiotensiniialfageneofthe1supstsuptypeinchildrenwithsecondaryhypertension AT vvdolgikh polymorphismofangiotensiniialfageneofthe1supstsuptypeinchildrenwithsecondaryhypertension AT taastakhova polymorphismofangiotensiniialfageneofthe1supstsuptypeinchildrenwithsecondaryhypertension AT vvalbot polymorphismofangiotensiniialfageneofthe1supstsuptypeinchildrenwithsecondaryhypertension AT evbelyaeva polymorphismofangiotensiniialfageneofthe1supstsuptypeinchildrenwithsecondaryhypertension |
| _version_ |
1718417131648843776 |