Gastrointestinal implications in COVID-19

Abstract Background Coronavirus disease 2019 (COVID-19 patients mostly present with respiratory symptoms; however, gastrointestinal (GI) manifestations can also be seen either alone or along with respiratory symptoms. We aimed to evaluate the GI symptoms related to COVID-19. Methods This cross-secti...

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Autores principales:	Ghazal Zoghi, Seyed Hamid Moosavy, Sadegh Yavarian, Mehdi HasaniAzad, Farid Khorrami, Masoud Sharegi Brojeni, Masoumeh Kheirandish
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Coronavirus SARS-CoV-2 Gastrointestinal symptoms Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/517efa005e9d4f69921019e88c597af7
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spelling	oai:doaj.org-article:517efa005e9d4f69921019e88c597af72021-11-08T11:18:41ZGastrointestinal implications in COVID-1910.1186/s12879-021-06824-y1471-2334https://doaj.org/article/517efa005e9d4f69921019e88c597af72021-11-01T00:00:00Zhttps://doi.org/10.1186/s12879-021-06824-yhttps://doaj.org/toc/1471-2334Abstract Background Coronavirus disease 2019 (COVID-19 patients mostly present with respiratory symptoms; however, gastrointestinal (GI) manifestations can also be seen either alone or along with respiratory symptoms. We aimed to evaluate the GI symptoms related to COVID-19. Methods This cross-sectional study retrospectively evaluated the medical files of 507 patients with confirmed or highly probable COVID-19. Based on their symptoms, patients were categorized into four groups: with GI symptoms alone (GIA), with respiratory symptoms alone (RA), with both GI and respiratory symptoms (GIR), and without GI or respiratory symptoms (WGIR). Results Of the 507 COVID-19 patients, 47.9% had at least one GI symptom; the most common was nausea and/or vomiting (31.6%). Patients in the GIA group were significantly older than those in the RA (P = 0.041) and GRI (P = 0.004) groups (54.70 ± 18.14 vs. 48.68 ± 14.67 and 46.80 ± 17.17 years, respectively). Groups were homogeneous with respect to gender. Leukopenia and lymphopenia were both less frequent in patients with GI symptoms compared to those without GI symptoms. Positive RT-PCR was significantly less frequent among patients with GI symptoms (44% vs. 100%, P < 0.001). Although mortality was lower in patients with GI symptoms (9.1%) in comparison with those without GI symptoms (13.3%), the difference was not statistically significant (P = 0.134). Conclusion The typical respiratory symptoms of COVID-19 are quite commonly accompanied by GI symptoms, with nausea and/or vomiting being the most prevalent. A subgroup of COVID-19 patients may exclusively present with GI symptoms. Special attention should be paid to these patients in order to avoid misdiagnosis or delayed treatment.Ghazal ZoghiSeyed Hamid MoosavySadegh YavarianMehdi HasaniAzadFarid KhorramiMasoud Sharegi BrojeniMasoumeh KheirandishBMCarticleCoronavirusSARS-CoV-2Gastrointestinal symptomsInfectious and parasitic diseasesRC109-216ENBMC Infectious Diseases, Vol 21, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Coronavirus SARS-CoV-2 Gastrointestinal symptoms Infectious and parasitic diseases RC109-216
spellingShingle	Coronavirus SARS-CoV-2 Gastrointestinal symptoms Infectious and parasitic diseases RC109-216 Ghazal Zoghi Seyed Hamid Moosavy Sadegh Yavarian Mehdi HasaniAzad Farid Khorrami Masoud Sharegi Brojeni Masoumeh Kheirandish Gastrointestinal implications in COVID-19
description	Abstract Background Coronavirus disease 2019 (COVID-19 patients mostly present with respiratory symptoms; however, gastrointestinal (GI) manifestations can also be seen either alone or along with respiratory symptoms. We aimed to evaluate the GI symptoms related to COVID-19. Methods This cross-sectional study retrospectively evaluated the medical files of 507 patients with confirmed or highly probable COVID-19. Based on their symptoms, patients were categorized into four groups: with GI symptoms alone (GIA), with respiratory symptoms alone (RA), with both GI and respiratory symptoms (GIR), and without GI or respiratory symptoms (WGIR). Results Of the 507 COVID-19 patients, 47.9% had at least one GI symptom; the most common was nausea and/or vomiting (31.6%). Patients in the GIA group were significantly older than those in the RA (P = 0.041) and GRI (P = 0.004) groups (54.70 ± 18.14 vs. 48.68 ± 14.67 and 46.80 ± 17.17 years, respectively). Groups were homogeneous with respect to gender. Leukopenia and lymphopenia were both less frequent in patients with GI symptoms compared to those without GI symptoms. Positive RT-PCR was significantly less frequent among patients with GI symptoms (44% vs. 100%, P < 0.001). Although mortality was lower in patients with GI symptoms (9.1%) in comparison with those without GI symptoms (13.3%), the difference was not statistically significant (P = 0.134). Conclusion The typical respiratory symptoms of COVID-19 are quite commonly accompanied by GI symptoms, with nausea and/or vomiting being the most prevalent. A subgroup of COVID-19 patients may exclusively present with GI symptoms. Special attention should be paid to these patients in order to avoid misdiagnosis or delayed treatment.
format	article
author	Ghazal Zoghi Seyed Hamid Moosavy Sadegh Yavarian Mehdi HasaniAzad Farid Khorrami Masoud Sharegi Brojeni Masoumeh Kheirandish
author_facet	Ghazal Zoghi Seyed Hamid Moosavy Sadegh Yavarian Mehdi HasaniAzad Farid Khorrami Masoud Sharegi Brojeni Masoumeh Kheirandish
author_sort	Ghazal Zoghi
title	Gastrointestinal implications in COVID-19
title_short	Gastrointestinal implications in COVID-19
title_full	Gastrointestinal implications in COVID-19
title_fullStr	Gastrointestinal implications in COVID-19
title_full_unstemmed	Gastrointestinal implications in COVID-19
title_sort	gastrointestinal implications in covid-19
publisher	BMC
publishDate	2021
url	https://doaj.org/article/517efa005e9d4f69921019e88c597af7
work_keys_str_mv	AT ghazalzoghi gastrointestinalimplicationsincovid19 AT seyedhamidmoosavy gastrointestinalimplicationsincovid19 AT sadeghyavarian gastrointestinalimplicationsincovid19 AT mehdihasaniazad gastrointestinalimplicationsincovid19 AT faridkhorrami gastrointestinalimplicationsincovid19 AT masoudsharegibrojeni gastrointestinalimplicationsincovid19 AT masoumehkheirandish gastrointestinalimplicationsincovid19
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Gastrointestinal implications in COVID-19

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