Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[ <i>a</i> ]Pyrene Metabolite Profile and Its Distribution in 3D Skin

Exposure to xenobiotics has repeatedly been associated with adverse health effects. While the majority of reported cases relate to direct substance effects, there is increasing evidence that microbiome-dependent metabolism of xenobiotic substances likewise has direct adverse effects on the host.

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Autores principales: Lisa Lemoine, Dilan Bayrambey, Alexander Roloff, Christoph Hutzler, Andreas Luch, Tewes Tralau
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/51a0375ce3404d2d9c86eb3b2d792af7
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spelling oai:doaj.org-article:51a0375ce3404d2d9c86eb3b2d792af72021-11-03T21:52:35Z Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[ <i>a</i> ]Pyrene Metabolite Profile and Its Distribution in 3D Skin 2150-751110.1128/mBio.01223-21https://doaj.org/article/51a0375ce3404d2d9c86eb3b2d792af72021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01223-21https://doaj.org/toc/2150-7511 Exposure to xenobiotics has repeatedly been associated with adverse health effects. While the majority of reported cases relate to direct substance effects, there is increasing evidence that microbiome-dependent metabolism of xenobiotic substances likewise has direct adverse effects on the host.Lisa LemoineDilan BayrambeyAlexander RoloffChristoph HutzlerAndreas LuchTewes TralauAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Lisa Lemoine
Dilan Bayrambey
Alexander Roloff
Christoph Hutzler
Andreas Luch
Tewes Tralau
Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[ <i>a</i> ]Pyrene Metabolite Profile and Its Distribution in 3D Skin
description Exposure to xenobiotics has repeatedly been associated with adverse health effects. While the majority of reported cases relate to direct substance effects, there is increasing evidence that microbiome-dependent metabolism of xenobiotic substances likewise has direct adverse effects on the host.
format article
author Lisa Lemoine
Dilan Bayrambey
Alexander Roloff
Christoph Hutzler
Andreas Luch
Tewes Tralau
author_facet Lisa Lemoine
Dilan Bayrambey
Alexander Roloff
Christoph Hutzler
Andreas Luch
Tewes Tralau
author_sort Lisa Lemoine
title Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[ <i>a</i> ]Pyrene Metabolite Profile and Its Distribution in 3D Skin
title_short Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[ <i>a</i> ]Pyrene Metabolite Profile and Its Distribution in 3D Skin
title_full Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[ <i>a</i> ]Pyrene Metabolite Profile and Its Distribution in 3D Skin
title_fullStr Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[ <i>a</i> ]Pyrene Metabolite Profile and Its Distribution in 3D Skin
title_full_unstemmed Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[ <i>a</i> ]Pyrene Metabolite Profile and Its Distribution in 3D Skin
title_sort commensal-related changes in the epidermal barrier function lead to alterations in the benzo[ <i>a</i> ]pyrene metabolite profile and its distribution in 3d skin
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/51a0375ce3404d2d9c86eb3b2d792af7
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