Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[ <i>a</i> ]Pyrene Metabolite Profile and Its Distribution in 3D Skin
Exposure to xenobiotics has repeatedly been associated with adverse health effects. While the majority of reported cases relate to direct substance effects, there is increasing evidence that microbiome-dependent metabolism of xenobiotic substances likewise has direct adverse effects on the host.
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American Society for Microbiology
2021
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oai:doaj.org-article:51a0375ce3404d2d9c86eb3b2d792af72021-11-03T21:52:35Z Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[ <i>a</i> ]Pyrene Metabolite Profile and Its Distribution in 3D Skin 2150-751110.1128/mBio.01223-21https://doaj.org/article/51a0375ce3404d2d9c86eb3b2d792af72021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01223-21https://doaj.org/toc/2150-7511 Exposure to xenobiotics has repeatedly been associated with adverse health effects. While the majority of reported cases relate to direct substance effects, there is increasing evidence that microbiome-dependent metabolism of xenobiotic substances likewise has direct adverse effects on the host.Lisa LemoineDilan BayrambeyAlexander RoloffChristoph HutzlerAndreas LuchTewes TralauAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021) |
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EN |
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Microbiology QR1-502 |
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Microbiology QR1-502 Lisa Lemoine Dilan Bayrambey Alexander Roloff Christoph Hutzler Andreas Luch Tewes Tralau Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[ <i>a</i> ]Pyrene Metabolite Profile and Its Distribution in 3D Skin |
description |
Exposure to xenobiotics has repeatedly been associated with adverse health effects. While the majority of reported cases relate to direct substance effects, there is increasing evidence that microbiome-dependent metabolism of xenobiotic substances likewise has direct adverse effects on the host. |
format |
article |
author |
Lisa Lemoine Dilan Bayrambey Alexander Roloff Christoph Hutzler Andreas Luch Tewes Tralau |
author_facet |
Lisa Lemoine Dilan Bayrambey Alexander Roloff Christoph Hutzler Andreas Luch Tewes Tralau |
author_sort |
Lisa Lemoine |
title |
Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[
<i>a</i>
]Pyrene Metabolite Profile and Its Distribution in 3D Skin
|
title_short |
Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[
<i>a</i>
]Pyrene Metabolite Profile and Its Distribution in 3D Skin
|
title_full |
Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[
<i>a</i>
]Pyrene Metabolite Profile and Its Distribution in 3D Skin
|
title_fullStr |
Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[
<i>a</i>
]Pyrene Metabolite Profile and Its Distribution in 3D Skin
|
title_full_unstemmed |
Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[
<i>a</i>
]Pyrene Metabolite Profile and Its Distribution in 3D Skin
|
title_sort |
commensal-related changes in the epidermal barrier function lead to alterations in the benzo[
<i>a</i>
]pyrene metabolite profile and its distribution in 3d skin |
publisher |
American Society for Microbiology |
publishDate |
2021 |
url |
https://doaj.org/article/51a0375ce3404d2d9c86eb3b2d792af7 |
work_keys_str_mv |
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1718445393504632832 |