Exploration of associations between deliberate self-poisoning and psychiatric disorders in rural Sri Lanka: A case-control study.

Psychiatric disorders are important predictors of deliberate self-harm. The present study was carried out to determine the associations between DSM-IV TR Axis- I & II disorders and deliberate self-poisoning (DSP) in a rural agricultural district in Sri Lanka. Patients residing in the district wh...

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Autores principales:	P H G J Pushpakumara, A H Dawson, A M P Adikari, S U B Thennakoon, Ranil Abeysinghe, T N Rajapakse
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/51a241c0ed5442aab3f32fe912e289fb
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spelling	oai:doaj.org-article:51a241c0ed5442aab3f32fe912e289fb2021-12-02T20:18:33ZExploration of associations between deliberate self-poisoning and psychiatric disorders in rural Sri Lanka: A case-control study.1932-620310.1371/journal.pone.0255805https://doaj.org/article/51a241c0ed5442aab3f32fe912e289fb2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0255805https://doaj.org/toc/1932-6203Psychiatric disorders are important predictors of deliberate self-harm. The present study was carried out to determine the associations between DSM-IV TR Axis- I & II disorders and deliberate self-poisoning (DSP) in a rural agricultural district in Sri Lanka. Patients residing in the district who presented with DSP were randomly selected for the study. Both the cases and age, sex, and, residential area, matched controls were assessed for DSM-IV TR Axis- I & II disorders based on the Structured Clinical Interview for DSM-IV-TR Axis I and II Disorders (SCID I & II) conducted by a specialist psychiatrist. Cases consisted of 208 (47.4%) males and 231 (52.6%) females. More than one third (37%) of males and more than half (53.7%) of females were aged below 20 years. DSM-IV TR axis-I and/or II psychiatric diagnoses were diagnosed in 89 (20.3%) of cases and 14 (3.2%) controls. Cases with a DSM-IV TR axis-I diagnosis were older than the cases without psychiatric diagnosis (32 and 19 years), p<0.0001. Having a depressive episode was associated with a 19 times higher risk for DSP. Being a male aged > = 30 years and having an alcohol use disorder carried a 21 times excess risk for DSP. A fivefold excess risk for DSP was found among 10-19 year old females with borderline personality traits. Depressive disorder and alcohol-related disorders were significantly associated with the older participants who presented with DSP. The overall prevalence of psychiatric disorders associated with DSP in rural Sri Lanka was significantly lower compared to the rates reported in the West and other countries in the region. Therefore, health and research priorities to reduce self-harm in Sri Lanka should focus both on psychiatric and non-psychiatric factors associated with DSP.P H G J PushpakumaraA H DawsonA M P AdikariS U B ThennakoonRanil AbeysingheT N RajapaksePublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 8, p e0255805 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q P H G J Pushpakumara A H Dawson A M P Adikari S U B Thennakoon Ranil Abeysinghe T N Rajapakse Exploration of associations between deliberate self-poisoning and psychiatric disorders in rural Sri Lanka: A case-control study.
description	Psychiatric disorders are important predictors of deliberate self-harm. The present study was carried out to determine the associations between DSM-IV TR Axis- I & II disorders and deliberate self-poisoning (DSP) in a rural agricultural district in Sri Lanka. Patients residing in the district who presented with DSP were randomly selected for the study. Both the cases and age, sex, and, residential area, matched controls were assessed for DSM-IV TR Axis- I & II disorders based on the Structured Clinical Interview for DSM-IV-TR Axis I and II Disorders (SCID I & II) conducted by a specialist psychiatrist. Cases consisted of 208 (47.4%) males and 231 (52.6%) females. More than one third (37%) of males and more than half (53.7%) of females were aged below 20 years. DSM-IV TR axis-I and/or II psychiatric diagnoses were diagnosed in 89 (20.3%) of cases and 14 (3.2%) controls. Cases with a DSM-IV TR axis-I diagnosis were older than the cases without psychiatric diagnosis (32 and 19 years), p<0.0001. Having a depressive episode was associated with a 19 times higher risk for DSP. Being a male aged > = 30 years and having an alcohol use disorder carried a 21 times excess risk for DSP. A fivefold excess risk for DSP was found among 10-19 year old females with borderline personality traits. Depressive disorder and alcohol-related disorders were significantly associated with the older participants who presented with DSP. The overall prevalence of psychiatric disorders associated with DSP in rural Sri Lanka was significantly lower compared to the rates reported in the West and other countries in the region. Therefore, health and research priorities to reduce self-harm in Sri Lanka should focus both on psychiatric and non-psychiatric factors associated with DSP.
format	article
author	P H G J Pushpakumara A H Dawson A M P Adikari S U B Thennakoon Ranil Abeysinghe T N Rajapakse
author_facet	P H G J Pushpakumara A H Dawson A M P Adikari S U B Thennakoon Ranil Abeysinghe T N Rajapakse
author_sort	P H G J Pushpakumara
title	Exploration of associations between deliberate self-poisoning and psychiatric disorders in rural Sri Lanka: A case-control study.
title_short	Exploration of associations between deliberate self-poisoning and psychiatric disorders in rural Sri Lanka: A case-control study.
title_full	Exploration of associations between deliberate self-poisoning and psychiatric disorders in rural Sri Lanka: A case-control study.
title_fullStr	Exploration of associations between deliberate self-poisoning and psychiatric disorders in rural Sri Lanka: A case-control study.
title_full_unstemmed	Exploration of associations between deliberate self-poisoning and psychiatric disorders in rural Sri Lanka: A case-control study.
title_sort	exploration of associations between deliberate self-poisoning and psychiatric disorders in rural sri lanka: a case-control study.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/51a241c0ed5442aab3f32fe912e289fb
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Exploration of associations between deliberate self-poisoning and psychiatric disorders in rural Sri Lanka: A case-control study.

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