Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity

Stress activates corticotropin-releasing hormone (CRH) neurons in the hypothalamus, but how their activity is regulated during and after stress is unclear. Here, the authors show that stress habituation and corticosteroid feedback tune different components of CRH neuron activity.

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Autores principales: Joon S. Kim, Su Young Han, Karl J. Iremonger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/51a4aad783fb4d5185a948f30135186c
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spelling oai:doaj.org-article:51a4aad783fb4d5185a948f30135186c2021-12-02T17:01:52ZStress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity10.1038/s41467-019-13639-82041-1723https://doaj.org/article/51a4aad783fb4d5185a948f30135186c2019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13639-8https://doaj.org/toc/2041-1723Stress activates corticotropin-releasing hormone (CRH) neurons in the hypothalamus, but how their activity is regulated during and after stress is unclear. Here, the authors show that stress habituation and corticosteroid feedback tune different components of CRH neuron activity.Joon S. KimSu Young HanKarl J. IremongerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Joon S. Kim
Su Young Han
Karl J. Iremonger
Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity
description Stress activates corticotropin-releasing hormone (CRH) neurons in the hypothalamus, but how their activity is regulated during and after stress is unclear. Here, the authors show that stress habituation and corticosteroid feedback tune different components of CRH neuron activity.
format article
author Joon S. Kim
Su Young Han
Karl J. Iremonger
author_facet Joon S. Kim
Su Young Han
Karl J. Iremonger
author_sort Joon S. Kim
title Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity
title_short Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity
title_full Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity
title_fullStr Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity
title_full_unstemmed Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity
title_sort stress experience and hormone feedback tune distinct components of hypothalamic crh neuron activity
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/51a4aad783fb4d5185a948f30135186c
work_keys_str_mv AT joonskim stressexperienceandhormonefeedbacktunedistinctcomponentsofhypothalamiccrhneuronactivity
AT suyounghan stressexperienceandhormonefeedbacktunedistinctcomponentsofhypothalamiccrhneuronactivity
AT karljiremonger stressexperienceandhormonefeedbacktunedistinctcomponentsofhypothalamiccrhneuronactivity
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