Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity
Stress activates corticotropin-releasing hormone (CRH) neurons in the hypothalamus, but how their activity is regulated during and after stress is unclear. Here, the authors show that stress habituation and corticosteroid feedback tune different components of CRH neuron activity.
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2019
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oai:doaj.org-article:51a4aad783fb4d5185a948f30135186c2021-12-02T17:01:52ZStress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity10.1038/s41467-019-13639-82041-1723https://doaj.org/article/51a4aad783fb4d5185a948f30135186c2019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13639-8https://doaj.org/toc/2041-1723Stress activates corticotropin-releasing hormone (CRH) neurons in the hypothalamus, but how their activity is regulated during and after stress is unclear. Here, the authors show that stress habituation and corticosteroid feedback tune different components of CRH neuron activity.Joon S. KimSu Young HanKarl J. IremongerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019) |
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Science Q Joon S. Kim Su Young Han Karl J. Iremonger Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity |
description |
Stress activates corticotropin-releasing hormone (CRH) neurons in the hypothalamus, but how their activity is regulated during and after stress is unclear. Here, the authors show that stress habituation and corticosteroid feedback tune different components of CRH neuron activity. |
format |
article |
author |
Joon S. Kim Su Young Han Karl J. Iremonger |
author_facet |
Joon S. Kim Su Young Han Karl J. Iremonger |
author_sort |
Joon S. Kim |
title |
Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity |
title_short |
Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity |
title_full |
Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity |
title_fullStr |
Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity |
title_full_unstemmed |
Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity |
title_sort |
stress experience and hormone feedback tune distinct components of hypothalamic crh neuron activity |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/51a4aad783fb4d5185a948f30135186c |
work_keys_str_mv |
AT joonskim stressexperienceandhormonefeedbacktunedistinctcomponentsofhypothalamiccrhneuronactivity AT suyounghan stressexperienceandhormonefeedbacktunedistinctcomponentsofhypothalamiccrhneuronactivity AT karljiremonger stressexperienceandhormonefeedbacktunedistinctcomponentsofhypothalamiccrhneuronactivity |
_version_ |
1718382028573900800 |