IL-10 mRNA Engineered MSCs Demonstrate Enhanced Anti-Inflammation in an Acute GvHD Model

Mesenchymal stem cells (MSCs) are used in various studies to induce immunomodulatory effects in clinical conditions associated with immune dysregulation such as graft versus host disease (GvHD). However, most of these clinical trials failed to go beyond early phase 2 studies because of limited effic...

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Autores principales: Cuiping Zhang, Mina Delawary, Peng Huang, Jennifer A. Korchak, Koji Suda, Abba C. Zubair
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/51a8916a21044af2ac4c6c0f1c2489c4
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