IL-10 mRNA Engineered MSCs Demonstrate Enhanced Anti-Inflammation in an Acute GvHD Model
Mesenchymal stem cells (MSCs) are used in various studies to induce immunomodulatory effects in clinical conditions associated with immune dysregulation such as graft versus host disease (GvHD). However, most of these clinical trials failed to go beyond early phase 2 studies because of limited effic...
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Main Authors: | Cuiping Zhang, Mina Delawary, Peng Huang, Jennifer A. Korchak, Koji Suda, Abba C. Zubair |
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Format: | article |
Language: | EN |
Published: |
MDPI AG
2021
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Online Access: | https://doaj.org/article/51a8916a21044af2ac4c6c0f1c2489c4 |
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